Mariana G Bego
Overview
Explore the profile of Mariana G Bego including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
525
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Recent Articles
1.
Polyak M, Abrahamyan L, Bego M
Front Immunol
. 2023 Apr;
14:1185693.
PMID: 37056777
No abstract available.
2.
Duarte N, Yanes-Lane M, Arora R, Bobrovitz N, Liu M, Bego M, et al.
Open Forum Infect Dis
. 2022 Feb;
9(2):ofab632.
PMID: 35103246
Population-level immune surveillance, which includes monitoring exposure and assessing vaccine-induced immunity, is a crucial component of public health decision-making during a pandemic. Serosurveys estimating the prevalence of severe acute respiratory...
3.
Wiche Salinas T, Gosselin A, Raymond Marchand L, Gabriel E, Tastet O, Goulet J, et al.
iScience
. 2021 Oct;
24(11):103225.
PMID: 34712922
The crosstalk between intestinal epithelial cells (IECs) and Th17-polarized CD4 T cells is critical for mucosal homeostasis, with HIV-1 causing significant alterations in people living with HIV (PLWH) despite antiretroviral...
4.
Bego M, Miguet N, Laliberte A, Aschman N, Gerard F, Merakos A, et al.
J Biol Chem
. 2019 May;
294(27):10503-10518.
PMID: 31118237
Type I interferons (IFN-I) are key innate immune effectors predominantly produced by activated plasmacytoid dendritic cells (pDCs). By modulating immune responses at their foundation, IFNs can widely reshape immunity to...
5.
Lodge R, Barbosa J, Lombard-Vadnais F, Gilmore J, Deshiere A, Gosselin A, et al.
Cell Rep
. 2017 Oct;
21(1):141-153.
PMID: 28978468
Macrophages are heterogeneous immune cells with distinct origins, phenotypes, functions, and tissue localization. Their susceptibility to HIV-1 is subject to variations from permissiveness to resistance, owing in part to regulatory...
6.
Yun T, Lee J, Machmach K, Shim D, Choi J, Wi Y, et al.
Cell Metab
. 2016 Dec;
24(6):886.
PMID: 27974180
No abstract available.
7.
Bego M, Cong L, Mack K, Kirchhoff F, Cohen E
J Virol
. 2016 Sep;
90(22):10236-10246.
PMID: 27581991
Importance: The geographical distributions and prevalences of different HIV-1 groups show large variations. Understanding drivers of distinctive viral spread may aid in the development of therapeutic strategies for controlling the...
8.
Yun T, Lee J, Machmach K, Shim D, Choi J, Wi Y, et al.
Cell Metab
. 2016 May;
23(5):852-66.
PMID: 27166946
Plasmacytoid dendritic cells (pDCs) are unique bone-marrow-derived cells that produce large amounts of type I interferon in response to microbial stimulation. Furthermore, pDCs also promote T cell tolerance in sterile-inflammation...
9.
Sugden S, Bego M, Pham T, Cohen E
Viruses
. 2016 Mar;
8(3):67.
PMID: 26950141
The plasma membrane protects the cell from its surroundings and regulates cellular communication, homing, and metabolism. Not surprisingly, the composition of this membrane is highly controlled through the vesicular trafficking...
10.
Bego M, Cote E, Cohen E
J Vis Exp
. 2015 Sep;
(103).
PMID: 26383704
HIV-1 innate sensing requires direct contact of infected CD4+ T cells with plasmacytoid dendritic cells (pDCs). In order to study this process, the protocols described here use freshly isolated human...