Marian Vincenzi
Overview
Explore the profile of Marian Vincenzi including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
86
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0
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Recent Articles
11.
Vincenzi M, Leone M
Curr Med Chem
. 2020 Dec;
28(22):4380-4453.
PMID: 33371830
Background: COVID-19 has brought the world to its knees, and there is an urgent need for new strategies to identify molecules capable of fighting the pandemic. During the last few...
12.
Vincenzi M, Mercurio F, Leone M
Curr Med Chem
. 2020 Jul;
28(14):2729-2782.
PMID: 32614739
Background: NMR spectroscopy is one of the most powerful tools to study the structure and interaction properties of peptides and proteins from a dynamic perspective. Knowing the bioactive conformations of...
13.
Vincenzi M, Mercurio F, Leone M
Curr Med Chem
. 2020 Jan;
28(5):854-892.
PMID: 31942846
Background: Proteins present a modular organization made up of several domains. Apart from the domains playing catalytic functions, many others are crucial to recruit interactors. The latter domains can be...
14.
Mercurio F, Di Natale C, Pirone L, Vincenzi M, Marasco D, De Luca S, et al.
Chembiochem
. 2019 Sep;
21(5):702-711.
PMID: 31538690
Sterile alpha motif (SAM) domains are protein interaction modules with a helical fold. SAM-SAM interactions often adopt the mid-loop (ML)/end-helix (EH) model, in which the C-terminal helix and adjacent loops...
15.
Vincenzi M, Mercurio F, Leone M
Curr Med Chem
. 2019 Jun;
27(37):6306-6355.
PMID: 31250750
Background: Many pathways regarding healthy cells and/or linked to diseases onset and progression depend on large assemblies including multi-protein complexes. Protein-protein interactions may occur through a vast array of modules...
16.
Vincenzi M, Mercurio F, Leone M
Curr Protein Pept Sci
. 2019 Feb;
20(5):425-451.
PMID: 30767740
The fluorinated alcohol 2,2,2-Trifluoroethanol (TFE) has been implemented for many decades now in conformational studies of proteins and peptides. In peptides, which are often disordered in aqueous solutions, TFE acts...
17.
Mercurio F, Di Natale C, Pirone L, Marasco D, Calce E, Vincenzi M, et al.
Bioorg Chem
. 2018 Dec;
84:434-443.
PMID: 30576907
EphA2 receptor plays a critical and debatable function in cancer and is considered a target in drug discovery. Lately, there has been a growing interest in its cytosolic C-terminal SAM...
18.
Vincenzi M, Mercurio F, Leone M
Curr Med Chem
. 2018 Oct;
27(3):450-476.
PMID: 30306850
Background: The sterile alpha motif (Sam) domain is a small helical protein module, able to undergo homo- and hetero-oligomerization, as well as polymerization, thus forming different types of protein architectures....
19.
Vincenzi M, Bednarska K, Lesnikowski Z
Molecules
. 2018 Jul;
23(8).
PMID: 30044380
Adenosine receptors are involved in many physiological processes and pathological conditions and are therefore attractive therapeutic targets. To identify new types of effective ligands for these receptors, a library of...
20.
Desplat V, Vincenzi M, Lucas R, Moreau S, Savrimoutou S, Rubio S, et al.
ChemMedChem
. 2017 Feb;
12(12):940-953.
PMID: 28218826
Acute leukemia is a hematological malignancy with high incidence and recurrence rates and is characterized by an accumulation of blasts in bone marrow due to proliferation of immature lymphoid or...