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Maria Victoria Sanchez-Gomez

Explore the profile of Maria Victoria Sanchez-Gomez including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 881
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Recent Articles
1.
Balantzategi U, Gaminde-Blasco A, Kearns C, Bayon-Cordero L, Sanchez-Gomez M, Zugaza J, et al.
Glia . 2025 Mar; PMID: 40087862
Soluble forms of amyloid-β (Aβ) peptide have been proposed as candidates to induce oligodendrocyte (OL) and myelin dysfunctions in the early stages of Alzheimer's disease (AD) pathology. Nevertheless, little is...
2.
Ayuso-Garcia P, Sanchez-Rueda A, Velasco-Aviles S, Tamayo-Caro M, Ferrer-Pinos A, Huarte-Sebastian C, et al.
Sci Adv . 2024 Apr; 10(15):eadm7600. PMID: 38608019
Myelination is essential for neuronal function and health. In peripheral nerves, >100 causative mutations have been identified that cause Charcot-Marie-Tooth disease, a disorder that can affect myelin sheaths. Among these,...
3.
Serrano-Regal M, Bayon-Cordero L, Chara Ventura J, Ochoa-Bueno B, Tepavcevic V, Matute C, et al.
Glia . 2022 Aug; 70(12):2426-2440. PMID: 35980256
Promoting remyelination is considered as a potential neurorepair strategy to prevent/limit the development of permanent neurological disability in patients with multiple sclerosis (MS). To this end, a number of clinical...
4.
Bayon-Cordero L, Ochoa-Bueno B, Ruiz A, Ozalla M, Matute C, Sanchez-Gomez M
Front Pharmacol . 2022 Aug; 13:897056. PMID: 35959434
Oligodendrocytes are the myelin forming cells of the central nervous system, and their vulnerability to excitotoxicity induced by glutamate contributes to the pathogenesis of neurological disorders including brain ischemia and...
5.
Ordaz R, Garay E, Limon A, Perez-Samartin A, Sanchez-Gomez M, Robles-Martinez L, et al.
Mol Pharmacol . 2020 Dec; 99(2):133-146. PMID: 33288547
Oligodendrocytes (OLs) express functional GABA receptors (GABARs) that are activated by GABA released at synaptic contacts with axons or by ambient GABA in extrasynaptic domains. In both instances, the receptors'...
6.
Serrano-Regal M, Bayon-Cordero L, Ordaz R, Garay E, Limon A, Arellano R, et al.
Front Cell Neurosci . 2020 Sep; 14:256. PMID: 32973453
Myelin facilitates the fast transmission of nerve impulses and provides metabolic support to axons. Differentiation of oligodendrocyte progenitor cells (OPCs) and Schwann cell (SC) precursors is critical for myelination during...
7.
Matute C, Palma A, Serrano-Regal M, Maudes E, Barman S, Sanchez-Gomez M, et al.
Ann Neurol . 2020 Feb; 87(5):670-676. PMID: 32052483
Objective: Antibodies against neuronal N-methyl-D-aspartate receptors (NMDARs) in patients with anti-NMDAR encephalitis alter neuronal synaptic function and plasticity, but the effects on other cells of the nervous system are unknown....
8.
Serrano-Regal M, Luengas-Escuza I, Bayon-Cordero L, Ibarra-Aizpurua N, Alberdi E, Perez-Samartin A, et al.
Neuroscience . 2019 Jul; 439:163-180. PMID: 31349008
Differentiation of oligodendrocyte precursor cells (OPCs) into mature oligodendrocytes (OLs) is a key event for axonal myelination in the central nervous system (CNS). Several growth factors and neurotransmitters like GABA...
9.
Quintela-Lopez T, Ortiz-Sanz C, Serrano-Regal M, Gaminde-Blasco A, Valero J, Baleriola J, et al.
Cell Death Dis . 2019 Jun; 10(6):445. PMID: 31171765
Alzheimer´s disease (AD) is characterized by a progressive cognitive decline that correlates with the levels of amyloid β-peptide (Aβ) oligomers. Strong evidences connect changes of oligodendrocyte function with the onset...
10.
Canedo-Antelo M, Serrano M, Manterola A, Ruiz A, Llavero F, Mato S, et al.
Front Mol Neurosci . 2018 Oct; 11:333. PMID: 30271323
Oligodendrocytes are highly vulnerable to glutamate excitotoxicity, a central mechanism involved in tissue damage in Multiple Sclerosis (MS). Sustained activation of AMPA receptors in rat oligodendrocytes induces cytosolic calcium overload,...