Elena Alberdi
Overview
Explore the profile of Elena Alberdi including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
1780
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0
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Recent Articles
1.
Balantzategi U, Gaminde-Blasco A, Kearns C, Bayon-Cordero L, Sanchez-Gomez M, Zugaza J, et al.
Glia
. 2025 Mar;
PMID: 40087862
Soluble forms of amyloid-β (Aβ) peptide have been proposed as candidates to induce oligodendrocyte (OL) and myelin dysfunctions in the early stages of Alzheimer's disease (AD) pathology. Nevertheless, little is...
2.
Cruz-Sese J, Miron-Alcala M, Alfonso-Triguero M, Olalde J, Ruiz L, Galbis-Gramage N, et al.
bioRxiv
. 2025 Feb;
PMID: 39975251
Despite strong evidence supporting that both astrocytes and apolipoprotein E (APOE) play crucial roles in the pathogenesis and progression of Alzheimer's disease (AD), the impact of astrocytes carrying different variants...
3.
Bonifazi G, Luchena C, Gaminde-Blasco A, Ortiz-Sanz C, Capetillo-Zarate E, Matute C, et al.
Neurobiol Dis
. 2024 Mar;
194:106473.
PMID: 38493903
The pathophysiological process of Alzheimer's disease (AD) is believed to begin many years before the formal diagnosis of AD dementia. This protracted preclinical phase offers a crucial window for potential...
4.
Alanko V, Gaminde-Blasco A, Quintela-Lopez T, Loera-Valencia R, Solomon A, Bjorkhem I, et al.
Glia
. 2023 Feb;
71(6):1414-1428.
PMID: 36779429
Oxidized cholesterol metabolite 27-hydroxycholesterol (27-OH) is a potential link between hypercholesterolemia and neurodegenerative diseases since unlike peripheral cholesterol, 27-OH is transported across the blood-brain barrier. However, the effects of high...
5.
Mendiguren A, Aostri E, Alberdi E, Perez-Samartin A, Pineda J
Front Pharmacol
. 2022 Sep;
13:956886.
PMID: 36147343
Cannabidiol (CBD), the main non-psychoactive cannabinoid found in the cannabis plant, elicits several pharmacological effects the 5-HT receptor. The dorsal raphe nucleus (DRN) is the main serotonergic cluster in the...
6.
Ortiz-Sanz C, Llavero F, Zuazo-Ibarra J, Balantzategi U, Quintela-Lopez T, Wyssenbach A, et al.
Int J Mol Sci
. 2022 May;
23(10).
PMID: 35628557
Glial cells participate actively in the early cognitive decline in Alzheimer's disease (AD) pathology. In fact, recent studies have found molecular and functional abnormalities in astrocytes and microglia in both...
7.
Luchena C, Zuazo-Ibarra J, Valero J, Matute C, Alberdi E, Capetillo-Zarate E
Front Aging Neurosci
. 2022 May;
14:844534.
PMID: 35493929
Glial cells are essential to understand Alzheimer's disease (AD) progression, given their role in neuroinflammation and neurodegeneration. There is a need for reliable and easy to manipulate models that allow...
8.
Ortiz-Sanz C, Balantzategi U, Quintela-Lopez T, Ruiz A, Luchena C, Zuazo-Ibarra J, et al.
Cell Death Dis
. 2022 Mar;
13(3):253.
PMID: 35306512
Amyloid beta (Aβ)-mediated synapse dysfunction is an early event in Alzheimer's disease (AD) pathogenesis and previous studies suggest that NMDA receptor (NMDAR) dysregulation may contribute to these pathological effects. Although...
9.
Blanco-Urrejola M, Gaminde-Blasco A, Gamarra M, de la Cruz A, Vecino E, Alberdi E, et al.
Cells
. 2021 Apr;
10(3).
PMID: 33809142
Cell polarity is crucial for almost every cell in our body to establish distinct structural and functional domains. Polarized cells have an asymmetrical morphology and therefore their proteins need to...
10.
Preman P, Alfonso-Triguero M, Alberdi E, Verkhratsky A, Arranz A
Cells
. 2021 Apr;
10(3).
PMID: 33806259
Astrocytes perform a wide variety of essential functions defining normal operation of the nervous system and are active contributors to the pathogenesis of neurodegenerative disorders such as Alzheimer's among others....