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Maria Lazarova

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Articles 21
Citations 89
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Recent Articles
1.
Lazarova M, Stefanova M, Tsvetanova E, Georgieva A, Tasheva K, Radeva L, et al.
Int J Mol Sci . 2024 Dec; 25(23). PMID: 39684486
Numerous experimental studies suggest the potential for resveratrol (RVT) to be useful in the Alzheimer's disease treatment, but its low bioavailability limits its application. This study aimed to assess the...
2.
Lazarova M, Stefanova M, Denev P, Taseva T, Vassileva V, Tasheva K
Biology (Basel) . 2024 Jun; 13(6). PMID: 38927306
The potential of to alleviate scopolamine (Sco)-induced deficits in spatial working memory has drawn considerable scientific interest. This effect is partly attributed to its potent antioxidant and acetylcholinesterase inhibitory (AChEI)...
3.
Lazarova M, Tsvetanova E, Georgieva A, Stefanova M, Uzunova D, Denev P, et al.
Int J Mol Sci . 2024 Feb; 25(3). PMID: 38339117
Griseb. and L., belonging to the Lamiaceae family, are rich in terpenoids and phenolics and exhibit various pharmacological effects, including antioxidant, anti-inflammatory and anti-cancer activities. While the memory-enhancing impacts of...
4.
Tancheva L, Kalfin R, Minchev B, Uzunova D, Tasheva K, Tsvetanova E, et al.
Antioxidants (Basel) . 2023 Dec; 12(12). PMID: 38136170
Alzheimer's disease manifests as a complex pathological condition, with neuroinflammation, oxidative stress and cholinergic dysfunction being a few of the many pathological changes. Due to the complexity of the disease,...
5.
Tasheva K, Georgieva A, Denev P, Dimitrova L, Dimitrova M, Misheva S, et al.
Plants (Basel) . 2023 Dec; 12(23). PMID: 38068562
Griseb. is a critically endangered Balkan endemic species, known for its antioxidant, neuroprotective and anti-inflammatory properties. The aim of the present study was to detail an efficient protocol for the...
6.
Petrova M, Dimitrova L, Dimitrova M, Denev P, Teneva D, Georgieva A, et al.
Plants (Basel) . 2023 Apr; 12(8). PMID: 37111815
L. is a valuable medicinal plant used for its anti-inflammatory, antibacterial and wound-healing properties. The present study describes an efficient protocol for the micropropagation of and compares, for the first...
7.
Kuhl T, Georgieva M, Hubner H, Lazarova M, Vogel M, Haas B, et al.
Eur J Med Chem . 2023 Apr; 254:115386. PMID: 37094450
The modulatory interactions between neurotensin (NT) and the dopaminergic neurotransmitter system in the brain suggest that NT may be associated with the progression of Parkinson's disease (PD). NT exerts its...
8.
Dragomanova S, Lazarova M, Munkuev A, Suslov E, Volcho K, Salakhutdinov N, et al.
Molecules . 2022 Sep; 27(17). PMID: 36080227
Methods: Scopolamine (Scop) was applied intraperitoneally in Wistar rats for 11 days, simultaneously with MACs or M as a referent, respectively. Brain acetylcholine esterase (AChE) activity, noradrenaline and serotonin levels,...
9.
Tancheva L, Lazarova M, Velkova L, Dolashki A, Uzunova D, Minchev B, et al.
J Alzheimers Dis . 2022 May; 88(1):155-175. PMID: 35599481
Background: Alzheimer's disease (AD) is a complex neurodegenerative disease with multifactorial etiology, unsatisfactory treatment, and a necessity for broad-spectrum active substances for cure. The mucus from Helix aspersa snail is...
10.
Dragomanova S, Pavlov S, Marinova D, Hodzev Y, Petralia M, Fagone P, et al.
Antioxidants (Basel) . 2022 Feb; 11(2). PMID: 35204256
There is growing attention on natural substances capable of stimulating the cholinergic system and of exerting antioxidant effects, as potential therapeutic agents in Alzheimer's disease (AD). The aim of the...