Maria Jose Ruiz-Hidalgo
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Explore the profile of Maria Jose Ruiz-Hidalgo including associated specialties, affiliations and a list of published articles.
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13
Citations
422
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Recent Articles
1.
Flores N, Fernandez-Aroca D, Garnes-Garcia C, Dominguez-Calvo A, Jimenez-Suarez J, Sabater S, et al.
Mol Oncol
. 2024 Dec;
PMID: 39626031
Pan-cyclin-dependent-kinase (CDK) inhibitors are a new class of targeted therapies that can act on multiple CDKs, with dinaciclib being one of the most promising compounds. Although used as a monotherapy,...
2.
Garcia-Flores N, Jimenez-Suarez J, Garnes-Garcia C, Fernandez-Aroca D, Sabater S, Andres I, et al.
Cancers (Basel)
. 2023 Feb;
15(3).
PMID: 36765819
Over the last 30 years, the study of the cellular response to ionizing radiation (IR) has increased exponentially. Among the various signaling pathways affected by IR, p38 MAPK has been...
3.
Arconada-Luque E, Jimenez-Suarez J, Pascual-Serra R, Nam-Cha S, Moline T, Cimas F, et al.
Cancers (Basel)
. 2022 Jul;
14(14).
PMID: 35884568
Sarcomas are a heterogeneous group of tumors in which the role of ERK5 is poorly studied. To clarify the role of this MAPK in sarcomatous pathology, we used a murine...
4.
Roche O, Fernandez-Aroca D, Arconada-Luque E, Garcia-Flores N, Mellor L, Ruiz-Hidalgo M, et al.
Int J Mol Sci
. 2020 Oct;
21(20).
PMID: 33053909
The p38 mitogen-activated protein kinase (MAPK) signaling pathway is implicated in cancer biology and has been widely studied over the past two decades as a potential therapeutic target. Most of...
5.
Ruiz-Garcia A, Lopez-Lopez S, Garcia-Ramirez J, Baladron V, Ruiz-Hidalgo M, Lopez-Sanz L, et al.
J Immunol
. 2016 Aug;
197(8):3371-3381.
PMID: 27574297
The involvement of NOTCH signaling in macrophage activation by Toll receptors has been clearly established, but the factors and pathways controlling NOTCH signaling during this process have not been completely...
6.
Garcia-Cano J, Ambroise G, Pascual-Serra R, Carrion M, Serrano-Oviedo L, Ortega-Muelas M, et al.
Oncotarget
. 2015 Jun;
6(17):15551-65.
PMID: 26036632
Resistance to cisplatin is a major challenge in the current cancer therapy. In order to explore new therapeutic strategies to cisplatin resistance, we evaluated, in a model of lung cancer...
7.
Rodriguez P, Higueras M, Gonzalez-Rajal A, Alfranca A, Fierro-Fernandez M, Garcia-Fernandez R, et al.
Cardiovasc Res
. 2011 Nov;
93(2):232-41.
PMID: 22068159
Aims: The epidermal growth factor-like protein Delta-like 1 (DLK1) regulates multiple differentiation processes. It resembles NOTCH ligands structurally and is considered a non-canonical ligand. Given the crucial role of the...
8.
Sanchez-Solana B, Nueda M, Ruvira M, Ruiz-Hidalgo M, Monsalve E, Rivero S, et al.
Biochim Biophys Acta
. 2011 Mar;
1813(6):1153-64.
PMID: 21419176
The protein DLK2, highly homologous to DLK1, belongs to the EGF-like family of membrane proteins, which includes NOTCH receptors and their DSL-ligands. The molecular mechanisms by which DLK proteins regulate...
9.
Monsalve E, Ruiz-Garcia A, Baladron V, Ruiz-Hidalgo M, Sanchez-Solana B, Rivero S, et al.
Eur J Immunol
. 2009 Aug;
39(9):2556-70.
PMID: 19662631
Macrophages present different Notch receptors and ligands on their surface. Following macrophage activation by LPS or other TLR ligands, Notch1 expression is upregulated. We report here that Notch signaling increases...
10.
Monsalve E, Perez M, Rubio A, Ruiz-Hidalgo M, Baladron V, Garcia-Ramirez J, et al.
J Immunol
. 2006 Apr;
176(9):5362-73.
PMID: 16622004
Notch signaling has been extensively implicated in cell-fate determination along the development of the immune system. However, a role for Notch signaling in fully differentiated immune cells has not been...