Maria Javier Ramirez
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Explore the profile of Maria Javier Ramirez including associated specialties, affiliations and a list of published articles.
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21
Citations
399
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Recent Articles
1.
Martinez-Lopez A, Reboredo C, Gonzalez-Navarro C, Solas M, Puerta E, Javier Ramirez M, et al.
Int J Pharm
. 2024 Oct;
666:124798.
PMID: 39366528
Empty zein nanoparticles (NP) have been shown to lower glycemia in rats by stimulating the secretion of endogenous GLP-1. This study evaluated the effect of these nanoparticles on the lifespan...
2.
Escalada P, Ezkurdia A, Javier Ramirez M, Solas M
Int J Mol Sci
. 2024 Feb;
25(3).
PMID: 38339177
One of the most biologically relevant functions of astrocytes within the CNS is the regulation of synaptic transmission, i.e., the physiological basis for information transmission between neurons. Changes in the...
3.
Perez-Silanes S, Martisova E, Moreno E, Solas M, Plano D, Sanmartin C, et al.
Int J Mol Sci
. 2024 Jan;
25(2).
PMID: 38255872
Alzheimer's disease (AD) is a complex and multifactorial neurodegenerative disorder characterized by cognitive decline, memory loss, behavioral changes, and other neurological symptoms. Considering the urgent need for new AD therapeutics,...
4.
Garcia-Osta A, Dong J, Moreno-Aliaga M, Javier Ramirez M
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35163135
The cell cycle consists of successive events that lead to the generation of new cells. The cell cycle is regulated by different cyclins, cyclin-dependent kinases (CDKs) and their inhibitors, such...
5.
Gil-Iturbe E, Solas M, Cuadrado-Tejedo M, Garcia-Osta A, Escote X, Javier Ramirez M, et al.
Mol Neurobiol
. 2019 Sep;
57(2):798-805.
PMID: 31473905
The brain depends on glucose as a source of energy. This implies the presence of glucose transporters, being GLUT1 and GLUT3 the most relevant. Expression of GLUT12 is found in...
6.
Gerenu G, Martisova E, Ferrero H, Carracedo M, Rantamaki T, Javier Ramirez M, et al.
Biochim Biophys Acta Mol Basis Dis
. 2017 Jan;
1863(4):991-1001.
PMID: 28132883
Brain-derived neurotrophic factor (BDNF) plays pivotal roles in neuronal function. The cleaved - mature - form of BDNF (mBDNF), predominantly expressed in adult brains, critically determines its effects. However, insufficient...
7.
Rodriguez-Perdigon M, Tordera R, Gil-Bea F, Gerenu G, Javier Ramirez M, Solas M
Hippocampus
. 2016 Jun;
26(10):1303-12.
PMID: 27258819
Alzheimer's disease (AD) is characterized phenotypically by memory impairment, histologically by accumulation of pTau and β-amyloid peptide and morphologically by a loss of nerve terminals in cortical and hippocampal regions....
8.
Rodriguez-Perdigon M, Solas M, Javier Ramirez M
J Alzheimers Dis
. 2016 Feb;
50(4):963-7.
PMID: 26836159
In the present work, the involvement of JNK in insulin signaling alterations and its role in glutamatergic deficits in Alzheimer's disease (AD) has been studied. In postmortem cortical tissues, pJNK...
9.
Rodriguez-Perdigon M, Solas M, Moreno-Aliaga M, Javier Ramirez M
Biochim Biophys Acta
. 2016 Jan;
1862(4):511-517.
PMID: 26769360
The concept of central insulin resistance and dysfunctional insulin signalling in sporadic Alzheimer's disease (AD) is now widely accepted and diabetes is recognized as one of the main risk factors...
10.
Javier Ramirez M
Alzheimers Res Ther
. 2013 Apr;
5(2):15.
PMID: 23607787
During the past 20 years, the 5-HT6 receptor has received increasing attention and become a promising target for improving cognition. Several studies with structurally different compounds have shown that not...