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Manuel Rodriguez-Perdigon

Explore the profile of Manuel Rodriguez-Perdigon including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 58
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Recent Articles
1.
Rodriguez-Perdigon M, Haeni L, Rothen-Rutishauser B, Ruegg C
Front Bioeng Biotechnol . 2023 Jun; 11:1159819. PMID: 37346794
The complex interaction between tumor-associated macrophages (TAMs) and tumor cells through soluble factors provides essential cues for breast cancer progression. TAMs-targeted therapies have shown promising clinical therapeutical potential against cancer...
2.
Rodriguez-Perdigon M, Jimaja S, Haeni L, Bruns N, Rothen-Rutishauser B, Ruegg C
Macromol Biosci . 2022 May; 22(8):e2200168. PMID: 35624036
The crosstalk between cancer cells and tumor associated macrophages (TAMs) within the tumor environment modulates tumor progression at all stages of cancer disease. TAMs are predominantly M2-like polarized macrophages with...
3.
Rodriguez-Perdigon M, Tordera R, Gil-Bea F, Gerenu G, Javier Ramirez M, Solas M
Hippocampus . 2016 Jun; 26(10):1303-12. PMID: 27258819
Alzheimer's disease (AD) is characterized phenotypically by memory impairment, histologically by accumulation of pTau and β-amyloid peptide and morphologically by a loss of nerve terminals in cortical and hippocampal regions....
4.
Rodriguez-Perdigon M, Solas M, Javier Ramirez M
J Alzheimers Dis . 2016 Feb; 50(4):963-7. PMID: 26836159
In the present work, the involvement of JNK in insulin signaling alterations and its role in glutamatergic deficits in Alzheimer's disease (AD) has been studied. In postmortem cortical tissues, pJNK...
5.
Rodriguez-Perdigon M, Solas M, Moreno-Aliaga M, Javier Ramirez M
Biochim Biophys Acta . 2016 Jan; 1862(4):511-517. PMID: 26769360
The concept of central insulin resistance and dysfunctional insulin signalling in sporadic Alzheimer's disease (AD) is now widely accepted and diabetes is recognized as one of the main risk factors...
6.
Bengoetxea X, Rodriguez-Perdigon M, Ramirez M
Front Biosci (Schol Ed) . 2015 May; 7(1):10-29. PMID: 25961683
Animal models are essential resources in basic research and drug discovery in the field of Alzheimer's disease (AD). As the main clinical feature in AD is cognitive failure, the ultimate...