Maria Isabel Hernandez-Alvarez
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Explore the profile of Maria Isabel Hernandez-Alvarez including associated specialties, affiliations and a list of published articles.
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32
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1699
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Recent Articles
1.
Cisa-Wieczorek S, Cisa-Wieczorek S, Hernandez-Alvarez M, Hernandez-Alvarez M, Parreno M, Parreno M, et al.
Exp Hematol
. 2025 Feb;
145:104748.
PMID: 39986568
The KIT receptor is a transmembrane protein found on the surface of many different cell types. Mutant forms of KIT are drivers of myeloid neoplasms, including systemic mastocytosis. The KIT...
2.
Castane H, Jimenez-Franco A, Hernandez-Aguilera A, Martinez-Navidad C, Cambra-Cortes V, Onoiu A, et al.
EBioMedicine
. 2024 Dec;
111():105532.
PMID: 39731853
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) and its more severe form steatohepatitis (MASH) contribute to rising morbidity and mortality rates. The storage of fat in humans is closely associated...
3.
Antelo-Cea D, Martinez-Rojas L, Cabrerizo-Ibanez I, Roudi Rashtabady A, Hernandez-Alvarez M
Int J Mol Sci
. 2024 Oct;
25(20).
PMID: 39457018
Obesity and type 2 diabetes (T2D) are widespread metabolic disorders that significantly impact global health today, affecting approximately 17% of adults worldwide with obesity and 9.3% with T2D. Both conditions...
4.
Borquez J, Diaz-Castro F, La Fuente F, Espinoza K, Figueroa A, Martinez-Ruiz I, et al.
Metabolism
. 2023 Dec;
152:155765.
PMID: 38142958
Background And Aim: The excessive accumulation of lipid droplets (LDs) is a defining characteristic of nonalcoholic fatty liver disease (NAFLD). The interaction between LDs and mitochondria is functionally important for...
5.
Jimenez-Franco A, Castane H, Martinez-Navidad C, Placed-Gallego C, Hernandez-Aguilera A, Fernandez-Arroyo S, et al.
Clin Nutr
. 2023 Dec;
43(1):246-258.
PMID: 38101315
Background: The relationship between lipid mediators and severe obesity remains unclear. Our study investigates the impact of severe obesity on plasma concentrations of oxylipins and fatty acids and explores the...
6.
Leiro M, Ventura R, Rojo-Querol N, Hernandez-Alvarez M
Bio Protoc
. 2023 Sep;
13(17):e4803.
PMID: 37719073
The subfractionation of the endoplasmic reticulum (ER) is a widely used technique in cell biology. However, current protocols present limitations such as low yield, the use of large number of...
7.
Naon D, Hernandez-Alvarez M, Shinjo S, Wieczor M, Ivanova S, Martins de Brito O, et al.
Science
. 2023 Jun;
380(6651):eadh9351.
PMID: 37347868
In eukaryotic cells, different organelles interact at membrane contact sites stabilized by tethers. Mitochondrial mitofusin 2 (MFN2) acts as a membrane tether that interacts with an unknown partner on the...
8.
Lopez-Soldado I, Torres A, Ventura R, Martinez-Ruiz I, Diaz-Ramos A, Planet E, et al.
Redox Biol
. 2023 Feb;
61:102630.
PMID: 36796135
Type 2 diabetes mellitus (T2D) affects millions of people worldwide and is one of the leading causes of morbidity and mortality. The skeletal muscle (SKM) is one of the most...
9.
Ventura R, Martinez-Ruiz I, Hernandez-Alvarez M
Biomedicines
. 2022 May;
10(5).
PMID: 35625937
Phospholipids are the basic structure block of eukaryotic membranes, in both the outer and inner membranes, which delimit cell organelles. Phospholipids can also be damaged by oxidative stress produced by...
10.
Diaz-Saez F, Blanco-Sinfreu C, Archilla-Ortega A, Sebastian D, Romero M, Hernandez-Alvarez M, et al.
Int J Mol Sci
. 2021 Dec;
22(23).
PMID: 34884763
The adipokine Neuregulin 4 (Nrg4) protects against obesity-induced insulin resistance. Here, we analyze how the downregulation of Nrg4 influences insulin action and the underlying mechanisms in adipocytes. Validated shRNA lentiviral...