Maria Grigoroiu-Serbanescu
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Explore the profile of Maria Grigoroiu-Serbanescu including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
OConnell K, Koromina M, van der Veen T, Boltz T, David F, Yang J, et al.
Nature
. 2025 Jan;
PMID: 39843750
Bipolar disorder is a leading contributor to the global burden of disease. Despite high heritability (60-80%), the majority of the underlying genetic determinants remain unknown. We analysed data from participants...
2.
Herrera-Rivero M, Adli M, Akiyama K, Akula N, Amare A, Ardau R, et al.
Int J Bipolar Disord
. 2024 Jun;
12(1):20.
PMID: 38865039
Background: Lithium (Li) remains the treatment of choice for bipolar disorders (BP). Its mood-stabilizing effects help reduce the long-term burden of mania, depression and suicide risk in patients with BP....
3.
Grigoroiu-Serbanescu M, van der Veen T, Bigdeli T, Herms S, Diaconu C, Neagu A, et al.
J Affect Disord
. 2024 Apr;
356:507-518.
PMID: 38640977
Aim: We investigated the predictive value of polygenic risk scores (PRS) derived from the schizophrenia GWAS (Trubetskoy et al., 2022) (SCZ3) for phenotypic traits of bipolar disorder type-I (BP-I) in...
4.
Koromina M, Ravi A, Panagiotaropoulou G, Schilder B, Humphrey J, Braun A, et al.
medRxiv
. 2024 Feb;
PMID: 38405768
Bipolar disorder (BD) is a heritable mental illness with complex etiology. While the largest published genome-wide association study identified 64 BD risk loci, the causal SNPs and genes within these...
5.
Ou A, Rosenthal S, Adli M, Akiyama K, Akula N, Alda M, et al.
Transl Psychiatry
. 2024 Feb;
14(1):109.
PMID: 38395906
Lithium is the gold standard treatment for bipolar disorder (BD). However, its mechanism of action is incompletely understood, and prediction of treatment outcomes is limited. In our previous multi-omics study...
6.
Herrera-Rivero M, Adli M, Akiyama K, Akula N, Amare A, Ardau R, et al.
Res Sq
. 2023 Dec;
PMID: 38077040
Background: Lithium (Li) remains the treatment of choice for bipolar disorders (BP). Its mood-stabilizing effects help reduce the long-term burden of mania, depression and suicide risk in patients with BP....
7.
Kelsoe J, Ou A, Rosenthal S, Adli M, Akiyama K, Akula N, et al.
Res Sq
. 2023 Oct;
PMID: 37886563
Lithium is the gold standard treatment for bipolar disorder (BD). However, its mechanism of action is incompletely understood, and prediction of treatment outcomes is limited. In our previous multi-omics study...
8.
Docherty A, Mullins N, Ashley-Koch A, Qin X, Coleman J, Shabalin A, et al.
Am J Psychiatry
. 2023 Oct;
180(10):723-738.
PMID: 37777856
Objective: Suicidal behavior is heritable and is a major cause of death worldwide. Two large-scale genome-wide association studies (GWASs) recently discovered and cross-validated genome-wide significant (GWS) loci for suicide attempt...
9.
Herrera-Rivero M, Gutierrez-Fragoso K, Thalamuthu A, Amare A, Adli M, Akiyama K, et al.
Res Sq
. 2023 Jul;
PMID: 37461719
The link between bipolar disorder (BP) and immune dysfunction remains controversial. While epidemiological studies have long suggested an association, recent research has found only limited evidence of such a relationship....
10.
Amare A, Thalamuthu A, Schubert K, Fullerton J, Ahmed M, Hartmann S, et al.
Mol Psychiatry
. 2023 Jul;
28(12):5251-5261.
PMID: 37433967
Lithium is regarded as the first-line treatment for bipolar disorder (BD), a severe and disabling mental health disorder that affects about 1% of the population worldwide. Nevertheless, lithium is not...