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Maria Gonzalez-Gonzalez

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Recent Articles
11.
Sierra-Sanchez A, Garrido-Martin D, Lourido L, Gonzalez-Gonzalez M, Diez P, Ruiz-Romero C, et al.
J Proteome Res . 2017 Apr; 16(5):1890-1899. PMID: 28379711
Osteoarthritis (OA) is one of the most prevalent articular diseases. The identification of proteins closely associated with the diagnosis, progression, prognosis, and treatment response is dramatically required for this pathology....
12.
Jara-Acevedo R, Diez P, Gonzalez-Gonzalez M, Degano R, Ibarrola N, Gongora R, et al.
Curr Pharm Des . 2016 Oct; 22(43):6490-6499. PMID: 27748198
The selection process aims sequential enrichment of phage antibody display library in clones that recognize the target of interest or antigen as the library undergoes successive rounds of selection. In...
13.
Diez P, Dasilva N, Gonzalez-Gonzalez M, Matarraz S, Casado-Vela J, Orfao A, et al.
Microarrays (Basel) . 2016 Sep; 1(2):64-83. PMID: 27605336
Microarrays constitute a new platform which allows the discovery and characterization of proteins. According to different features, such as content, surface or detection system, there are many types of protein...
14.
Diez P, Gonzalez-Gonzalez M, Lourido L, Degano R, Ibarrola N, Casado-Vela J, et al.
Microarrays (Basel) . 2016 Sep; 4(2):214-27. PMID: 27600221
Nucleic Acid Programmable Protein Arrays (NAPPA) have emerged as a powerful and innovative technology for the screening of biomarkers and the study of protein-protein interactions, among others possible applications. The...
15.
Diez P, Lorenzo S, Degano R, Ibarrola N, Gonzalez-Gonzalez M, Nieto W, et al.
Proteomics . 2016 Feb; 16(8):1193-203. PMID: 26910488
Chronic lymphocytic leukaemia (CLL) is a malignant B cell disorder characterized by its high heterogeneity. Although genomic alterations have been broadly reported, protein studies are still in their early stages....
16.
Diez P, Jara-Acevedo R, Gonzalez-Gonzalez M, Casado-Vela J, Dasilva N, Lecrevisse Q, et al.
Enzyme Microb Technol . 2015 Sep; 79-80:34-41. PMID: 26320712
Emerging technologies for the design and generation of human antibodies require improved approaches enabling their screening, characterization and validation. Currently, strategies based on ELISA or western blot are used to...
17.
Horvatovich P, Vegvari A, Saul J, Park J, Qiu J, Syring M, et al.
J Proteome Res . 2015 Jul; 14(9):3441-51. PMID: 26155874
Approximately 18% of all human genes purported to encode proteins have not been directly evidenced at the protein level, according to the validation criteria established by neXtProt, and are considered...
18.
Horvatovich P, Lundberg E, Chen Y, Sung T, He F, Nice E, et al.
J Proteome Res . 2015 Jun; 14(9):3415-31. PMID: 26076068
This paper summarizes the recent activities of the Chromosome-Centric Human Proteome Project (C-HPP) consortium, which develops new technologies to identify yet-to-be annotated proteins (termed "missing proteins") in biological samples that...
19.
Gonzalez-Gonzalez M, Garcia J, Alcazar J, Gutierrez M, Gonzalez L, Bengoechea O, et al.
Medicine (Baltimore) . 2014 Dec; 93(26):e153. PMID: 25474426
Neoadjuvant radiochemotherapy to locally advanced rectal carcinoma patients has proven efficient in a high percentage of cases. Despite this, some patients show nonresponse or even disease progression. Recent studies suggest...
20.
Henjes F, Lourido L, Ruiz-Romero C, Fernandez-Tajes J, Schwenk J, Gonzalez-Gonzalez M, et al.
J Proteome Res . 2014 Sep; 13(11):5218-29. PMID: 25227461
Osteoarthritis (OA) is the most common rheumatic disease and one of the most disabling pathologies worldwide. To date, the diagnostic methods of OA are very limited, and there are no...