Maria Dux
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Explore the profile of Maria Dux including associated specialties, affiliations and a list of published articles.
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29
Citations
507
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Recent Articles
1.
Benedicter N, Vogler B, Kuhn A, Schramm J, Mackenzie K, Stratton J, et al.
Cells
. 2024 Apr;
13(7.
PMID: 38607011
Calcitonin gene-related peptide (CGRP) and nitric oxide (NO) have been recognized as important mediators in migraine but their mechanisms of action and interaction have not been fully elucidated. Monoclonal anti-CGRP...
2.
Friedrich N, Nemeth K, Tanner M, Rosta J, Dobos I, Oszlacs O, et al.
J Headache Pain
. 2024 Jan;
25(1):9.
PMID: 38243174
Background: Monoclonal antibodies directed against the neuropeptide calcitonin gene-related peptide (CGRP) are effective in the prevention of chronic and frequent episodic migraine. Since the antibodies do not cross the blood...
3.
Vogler B, Kuhn A, Mackenzie K, Stratton J, Dux M, Messlinger K
Int J Mol Sci
. 2023 Sep;
24(17).
PMID: 37686275
Treatment with the anti-CGRP antibody fremanezumab is successful in the prevention of chronic and frequent episodic migraine. In preclinical rat experiments, fremanezumab has been shown to reduce calcitonin gene-related peptide...
4.
Benedicter N, Messlinger K, Vogler B, Mackenzie K, Stratton J, Friedrich N, et al.
Neurol Int
. 2023 May;
15(2):622-637.
PMID: 37218978
Migraine pain is frequently accompanied by cranial hyperalgesia and allodynia. Calcitonin gene-related peptide (CGRP) is implicated in migraine pathophysiology but its role in facial hypersensitivity is not entirely clear. In...
5.
Santha P, Lakatos S, Horvath A, Dux M, Jancso G
Biomedicines
. 2022 Jun;
10(6).
PMID: 35740347
Perineural treatment of peripheral nerves with capsaicin produces a long-lasting selective regional thermo- and chemo-analgesia and elimination of the neurogenic inflammatory response involving degeneration of nociceptive afferent fibers. In this...
6.
The Anti-CGRP Antibody Fremanezumab Lowers CGRP Release from Rat Dura Mater and Meningeal Blood Flow
Dux M, Vogler B, Kuhn A, Mackenzie K, Stratton J, Messlinger K
Cells
. 2022 Jun;
11(11).
PMID: 35681463
Monoclonal antibodies directed against the neuropeptide calcitonin gene-related peptide (CGRP) belong to a new generation of therapeutics that are effective in the prevention of migraine. CGRP, a potent vasodilator, is...
7.
Rosta J, Toth M, Friedrich N, Santha P, Jancso G, Dux M
J Headache Pain
. 2022 Jan;
23(1):7.
PMID: 35033025
Background: Clinical observations suggest that hyperinsulinemia and insulin resistance can be associated with migraine headache. In the present study we examined the effect of insulin on transient receptor potential vanilloid...
8.
Risch M, Vogler B, Dux M, Messlinger K
J Headache Pain
. 2021 Sep;
22(1):105.
PMID: 34496764
Background: Calcitonin gene-related peptide (CGRP) is released from activated meningeal afferent fibres in the cranial dura mater, which likely accompanies severe headache attacks. Increased CGRP levels have been observed in...
9.
Lengyel M, Hajdu D, Dobolyi A, Rosta J, Czirjak G, Dux M, et al.
Cephalalgia
. 2021 Feb;
41(7):827-838.
PMID: 33525904
Background: TWIK-related spinal cord potassium channel (TRESK) background potassium channels have a key role in controlling resting membrane potential and excitability of sensory neurons. A frameshift mutation leading to complete...
10.
Dux M, Rosta J, Messlinger K
Int J Mol Sci
. 2020 Jan;
21(1).
PMID: 31948011
Pain in trigeminal areas is driven by nociceptive trigeminal afferents. Transduction molecules, among them the nonspecific cation channels transient receptor potential vanilloid 1 (TRPV1) and ankyrin 1 (TRPA1), which are...