Maria Claudia Gonzalez Deniselle
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Explore the profile of Maria Claudia Gonzalez Deniselle including associated specialties, affiliations and a list of published articles.
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Citations
545
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Recent Articles
1.
Esperante I, Meyer M, Banzan C, Kruse M, Lima A, Roig P, et al.
Biomolecules
. 2024 Apr;
14(4).
PMID: 38672445
Amyotrophic lateral sclerosis (ALS) is a fatal motoneuron degenerative disease that is associated with demyelination. The () mouse exhibits motoneuron degeneration, gliosis and myelin deterioration in the cervical spinal cord....
2.
Rey M, Coirini H, Marchena A, Deniselle M, Kruse M
J Neuroendocrinol
. 2023 Dec;
36(2):e13362.
PMID: 38148478
Excessive consumption of sugary drinks negatively impacts the developing brain, producing long-lasting behavioral and metabolic disorders. Here, we study whether treatment with the antihyperglycemic agent metformin prevents some of the...
3.
Meyer M, Meijer O, Hunt H, Belanoff J, Lima A, de Kloet E, et al.
Mol Neurobiol
. 2023 Aug;
61(1):1-14.
PMID: 37566177
Glucocorticoids exert antiinflammatory, antiproliferative and immunosupressive effects. Paradoxically they may also enhance inflammation particularly in the nervous system, as shown in Cushing´ syndrome and neurodegenerative disorders of humans and models...
4.
Coirini H, Rey M, Deniselle M, Kruse M
Biomedicines
. 2022 Nov;
10(11).
PMID: 36359243
We previously described that excessive consumption of sucrose during youth produces fear memory and anxiety-like behavior in adulthood. Here, we evaluated whether high cognitive function is also affected by studying...
5.
Meyer M, Lima A, Deniselle M, De Nicola A
Cell Mol Neurobiol
. 2022 Oct;
43(5):2149-2163.
PMID: 36219378
The Wobbler mouse is an accepted model of sporadic amyotrophic lateral sclerosis. The spinal cord of clinically symptomatic animals (3-5 months old) shows vacuolar motoneuron degeneration, inflammation, and gliosis accompanied...
6.
De Nicola A, Meyer M, Garay L, Kruse M, Schumacher M, Guennoun R, et al.
Cell Mol Neurobiol
. 2021 Jun;
42(1):23-40.
PMID: 34138412
Progesterone regulates a number of processes in neurons and glial cells not directly involved in reproduction or sex behavior. Several neuroprotective effects are better observed under pathological conditions, as shown...
7.
Lara A, Esperante I, Meyer M, Liere P, Di Giorgio N, Schumacher M, et al.
Mol Neurobiol
. 2021 Jan;
58(5):2088-2106.
PMID: 33411236
Patients suffering of amyotrophic lateral sclerosis (ALS) present motoneuron degeneration leading to muscle atrophy, dysphagia, and dysarthria. The Wobbler mouse, an animal model of ALS, shows a selective loss of...
8.
De Nicola A, Meyer M, Guennoun R, Schumacher M, Hunt H, Belanoff J, et al.
Int J Mol Sci
. 2020 Apr;
21(6).
PMID: 32244957
Glucocorticoids are crucial for stress-coping, resilience, and adaptation. However, if the stress hormones become dysregulated, the vulnerability to stress-related diseases is enhanced. In this brief review, we discuss the role...
9.
Meyer M, Kruse M, Garay L, Lima A, Roig P, Hunt H, et al.
Brain Res
. 2019 Nov;
1727:146551.
PMID: 31726042
The Wobbler mouse spinal cord shows vacuolated motoneurons, glial reaction, inflammation and abnormal glutamatergic parameters. Wobblers also show deficits of motor performance. These conditions resemble amyotrophic lateral sclerosis (ALS). Wobbler...
10.
Gargiulo-Monachelli G, Meyer M, Lara A, Garay L, Lima A, Roig P, et al.
J Steroid Biochem Mol Biol
. 2019 Jun;
192:105385.
PMID: 31150830
The Wobbler mouse has been proposed as an experimental model of the sporadic form of amyotrophic lateral sclerosis (ALS). The administration of natural progesterone (PROG) to Wobbler mice attenuates neuropathology,...