Maria Claudia Gonzalez Deniselle
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Explore the profile of Maria Claudia Gonzalez Deniselle including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
De Nicola A, Deniselle M
Cell Mol Neurobiol
. 2019 Apr;
39(4):471-472.
PMID: 30941611
Steroids are complex molecules, exerting known and still unknown effects in the nervous system. Throughout this volume, the reader will find a wide spectrum of articles, giving an up-to-date account...
12.
Meyer M, Lara A, Hunt H, Belanoff J, de Kloet E, Deniselle M, et al.
Neuroscience
. 2018 Jun;
384:384-396.
PMID: 29890290
Wobbler mice are experimental models for amyotrophic lateral sclerosis. As such they show motoneuron degeneration, motor deficits, and astrogliosis and microgliosis of the spinal cord. Additionally, Wobbler mice show increased...
13.
Meyer M, Garay L, Kruse M, Lara A, Gargiulo-Monachelli G, Schumacher M, et al.
J Steroid Biochem Mol Biol
. 2017 Sep;
174:201-216.
PMID: 28951257
Amyotrophic lateral sclerosis (ALS) is a devastating disorder characterized by progressive death of motoneurons. The Wobbler (WR) mouse is a preclinical model sharing neuropathological similarities with human ALS. We have...
14.
Casas S, Deniselle M, Gargiulo-Monachelli G, Perez A, Tourreilles M, Mattiazzi M, et al.
Horm Metab Res
. 2016 Nov;
49(1):16-22.
PMID: 27813048
Despite several scientific and technological advances, there is no single neuroprotective treatment that can reverse the brain damage after acute ischemic stroke (AIS). Neuroactive steroids are cholesterol-derived hormones that have...
15.
Garay L, Gonzalez Giqueaux P, Guennoun R, Schumacher M, Deniselle M, De Nicola A
J Steroid Biochem Mol Biol
. 2016 Sep;
165(Pt B):421-429.
PMID: 27597394
Previous studies of experimental autoimmune encephalomyelitis (EAE) have shown that progesterone decreases inflammatory cell infiltration and proinflammatory factors, increases myelination and attenuates clinical grade of EAE mice. To elucidate potential...
16.
Deniselle M, Liere P, Pianos A, Meyer M, Aprahamian F, Cambourg A, et al.
Endocrinology
. 2016 Aug;
157(11):4446-4460.
PMID: 27571131
The Wobbler mouse is an animal model for human motoneuron diseases, especially amyotrophic lateral sclerosis (ALS), used in the investigation of both pathology and therapeutic treatment. ALS is a fatal...
17.
Garay L, Deniselle M, Gierman L, Lima A, Roig P, De Nicola A
Horm Mol Biol Clin Investig
. 2015 May;
1(1):43-51.
PMID: 25961971
Background: Pregnant women with multiple sclerosis (MS) show disease remission in the third trimester concomitant with high circulating levels of sex steroids. Rodent experimental autoimmune encephalomyelitis (EAE) is an accepted...
18.
Monachelli G, Meyer M, Rodriguez G, Garay L, Sica R, De Nicola A, et al.
Horm Mol Biol Clin Investig
. 2015 May;
6(1):167-73.
PMID: 25961252
Unlabelled: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder. Worse prognostic factors in ALS are: (a) advanced age, (b) bulbar onset, and (c) short time between onset and diagnosis. Progesterone...
19.
Garay L, Deniselle M, Sitruk-Ware R, Guennoun R, Schumacher M, De Nicola A
J Neuroimmunol
. 2014 Sep;
276(1-2):89-97.
PMID: 25200475
Progesterone plays a protective role in the experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis (MS). Besides spinal cord neuropathology, MS patients present a dysfunctional hippocampus. In this work we...
20.
Meyer M, Deniselle M, Hunt H, de Kloet E, De Nicola A
J Steroid Biochem Mol Biol
. 2014 Feb;
143:40-8.
PMID: 24565565
Mutant Wobbler mice are models for human amyotrophic lateral sclerosis (ALS). In addition to spinal cord degeneration, Wobbler mice show high levels of blood corticosterone, hyperactivity of the hypothalamic-pituitary-adrenal axis...