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Maria C Heidkamp

Explore the profile of Maria C Heidkamp including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 179
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Recent Articles
1.
Hart D, Heidkamp M, Iyengar R, Vijayan K, Szotek E, Barakat J, et al.
J Mol Cell Cardiol . 2008 May; 45(1):93-105. PMID: 18495152
PYK2 is a Ca(2+)-dependent, nonreceptor protein tyrosine kinase that is involved in the induction of left ventricular hypertrophy (LVH) and its transition to heart failure. We and others have previously...
2.
Heidkamp M, Iyengar R, Szotek E, Cribbs L, Samarel A
J Mol Cell Cardiol . 2006 Dec; 42(2):422-31. PMID: 17157309
The myristoylated, alanine-rich protein kinase C substrate (MARCKS) is a cytoskeletal protein implicated in the regulation of cell spreading, stress fiber formation, and focal adhesion assembly in nonmuscle cells. However,...
3.
Heidkamp M, Scully B, Vijayan K, Engman S, Szotek E, Samarel A
Am J Physiol Cell Physiol . 2005 Apr; 289(2):C471-82. PMID: 15829561
The nonreceptor protein tyrosine kinase (PTK) proline-rich tyrosine kinase 2 (PYK2) has been implicated in cell signaling pathways involved in left ventricular hypertrophy and heart failure, but its exact role...
4.
Bayer A, Heidkamp M, Howes A, Brown J, Byron K, Samarel A
J Mol Cell Cardiol . 2003 Sep; 35(9):1121-33. PMID: 12967635
Proline-rich tyrosine kinase 2 (PYK2) is a nonreceptor protein tyrosine kinase that links G-protein-coupled receptors to activation of MAPK cascades and cellular growth. In smooth muscle and other cell types,...
5.
Heidkamp M, Bayer A, Scully B, Eble D, Samarel A
Am J Physiol Heart Circ Physiol . 2003 Jun; 285(4):H1684-96. PMID: 12829427
Focal adhesion kinase (FAK) is a nonreceptor protein tyrosine kinase critical for both cardiomyocyte survival and sarcomeric assembly during endothelin (ET)-induced cardiomyocyte hypertrophy. ET-induced FAK activation requires upstream activation of...
6.
Bayer A, Heidkamp M, Patel N, Porter M, Engman S, Samarel A
Mol Cell Biochem . 2003 Mar; 242(1-2):145-52. PMID: 12619877
Cardiomyocytes express several isoenzymes of protein kinase C (PKC), which as a group have been implicated in the induction of left ventricular hypertrophy (LVH) and its transition to heart failure....
7.
Porter M, Heidkamp M, Scully B, Patel N, Martin J, Samarel A
Am J Physiol Cell Physiol . 2003 Feb; 285(1):C39-47. PMID: 12606313
Patients with cardiac hypertrophy and heart failure display abnormally slowed myocardial relaxation, which is associated with downregulation of sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA2) gene expression. We previously showed that SERCA2 downregulation...
8.
Bayer A, Heidkamp M, Patel N, Porter M, Engman S, Samarel A
Am J Physiol Heart Circ Physiol . 2002 Jul; 283(2):H695-706. PMID: 12124218
Proline-rich tyrosine kinase 2 (PYK2) is a member of the focal adhesion kinase (FAK) family of nonreceptor protein tyrosine kinases. PYK2 has been implicated in linking G protein-coupled receptors to...
9.
Heidkamp M, Bayer A, Kalina J, Eble D, Samarel A
Circ Res . 2002 Jun; 90(12):1282-9. PMID: 12089066
Focal adhesion kinase (FAK) is a nonreceptor protein tyrosine kinase involved in adhesion-dependent signal transduction. FAK is highly expressed in cultured neonatal rat ventricular myocytes (NRVMs) and undergoes tyrosine autophosphorylation...