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Maria Bhat

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Articles 15
Citations 609
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Recent Articles
1.
Armisen J, Rauschecker M, Sarv J, Liljeblad M, Wernevik L, Niazi M, et al.
J Hepatol . 2025 Jan; PMID: 39798707
Background & Aims: A common genetic variant (rs738409) encoding isoleucine to methionine at position 148 in the PNPLA3 protein is a determinant of hepatic steatosis, inflammation, fibrosis, cirrhosis, and liver-related...
2.
Hofherr A, Liarte Marin E, Musial B, Seth A, Slidel T, Conway J, et al.
Kidney Int Rep . 2024 Jun; 9(6):1876-1891. PMID: 38899206
Introduction: Inflammation is a significant contributor to cardiorenal morbidity and mortality in diabetic kidney disease (DKD). The pathophysiological mechanisms linking systemic, subacute inflammation and local, kidney injury-initiated immune maladaptation is...
3.
Lofgren L, von Euler Chelpin M, Bhat M, Althage M, Hober A, Edfors F, et al.
J Appl Lab Med . 2023 Dec; 9(2):329-341. PMID: 38113397
Background: Developing and implementing new patient-centric strategies for drug trials lowers the barrier to participation for some patients by reducing the need to travel to research sites. In early chronic...
4.
Shang P, Ho A, Tufvesson-Alm M, Lindberg D, Grant C, Orhan F, et al.
Transl Psychiatry . 2022 Jun; 12(1):229. PMID: 35665740
Psychotic disorders are currently diagnosed by examining the patient's mental state and medical history. Identifying reliable diagnostic, monitoring, predictive, or prognostic biomarkers would be useful in clinical settings and help...
5.
Sellgren C, Imbeault S, Larsson M, Oliveros A, Nilsson I, Codeluppi S, et al.
Mol Psychiatry . 2021 Nov; 27(3):1855. PMID: 34744164
No abstract available.
6.
Sellgren C, Imbeault S, Larsson M, Oliveros A, Nilsson I, Codeluppi S, et al.
Mol Psychiatry . 2021 May; 26(11):6820-6832. PMID: 33976392
The G protein-coupled receptor kinase (GRK) family member protein GRK3 has been linked to the pathophysiology of schizophrenia and bipolar disorder. Expression, as well as protein levels, of GRK3 are...
7.
Naz S, Bhat M, Stahl S, Forsslund H, Skold C, Wheelock A, et al.
Metabolites . 2019 Oct; 9(10). PMID: 31581603
Increased activity of indoleamine 2,3-dioxygenase (IDO) and tryptophan hydroxylase (TPH) have been reported in individuals with chronic obstructive pulmonary disease (COPD). We therefore investigated the effect of gender stratification upon...
8.
Johansson V, Erhardt S, Engberg G, Kegel M, Bhat M, Schwieler L, et al.
Eur Arch Psychiatry Clin Neurosci . 2019 Jul; 270(7):933-938. PMID: 31302732
Preclinical studies indicate a link between the kynurenine pathway and monocyte chemoattractant protein-1 (MCP-1), but there is a lack of clinical studies examining this further. We here perform a secondary...
9.
Bhat M, Lindgren A, Eketjall S, Hidi R, Schatz P, Whatling C, et al.
Bioanalysis . 2019 Jun; 11(11):1055-1066. PMID: 31251101
To develop a high sensitivity and specific analytical method to measure endogenous levels of leukotriene B4 (LTB) in human plasma. LC-MS/MS and ELISA. An LC-MS/MS method was developed with a...
10.
Ericsson H, Nelander K, Lagerstrom-Fermer M, Balendran C, Bhat M, Chialda L, et al.
Clin Transl Sci . 2018 Mar; 11(3):330-338. PMID: 29517132
We evaluated safety, tolerability, pharmacokinetics, and pharmacodynamics of AZD5718, a novel 5-lipooxygenase activating protein (FLAP) inhibitor, in a randomized, single-blind, placebo-controlled, first-in-human (FIH) study consisting of single and multiple ascending...