Margreet Brouwer
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Explore the profile of Margreet Brouwer including associated specialties, affiliations and a list of published articles.
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10
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470
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Recent Articles
1.
Preillon J, Cuende J, Rabolli V, Garnero L, Mercier M, Wald N, et al.
Mol Cancer Ther
. 2020 Dec;
20(1):121-131.
PMID: 33277440
TIGIT is an immune checkpoint inhibitor expressed by effector CD4 and CD8 T cells, NK cells, and regulatory T cells (Tregs). Inhibition of TIGIT-ligand binding using antagonistic anti-TIGIT mAbs has...
2.
Verstichel G, Vermijlen D, Martens L, Goetgeluk G, Brouwer M, Thiault N, et al.
Sci Immunol
. 2017 Aug;
2(8).
PMID: 28783686
The thymus plays a central role in self-tolerance, partly by eliminating precursors with a T cell receptor (TCR) that binds strongly to self-antigens. However, the generation of self-agonist-selected lineages also...
3.
Dimova T, Brouwer M, Gosselin F, Tassignon J, Leo O, Donner C, et al.
Proc Natl Acad Sci U S A
. 2015 Jan;
112(6):E556-65.
PMID: 25617367
γδ T cells are unconventional T cells recognizing antigens via their γδ T-cell receptor (TCR) in a way that is fundamentally different from conventional αβ T cells. γδ T cells...
4.
Moens E, Brouwer M, Dimova T, Goldman M, Willems F, Vermijlen D
J Leukoc Biol
. 2011 Feb;
89(5):743-52.
PMID: 21330350
The immune system in early life is regarded as immature. However, the IL-12 family member IL-23 is highly produced upon TLR stimulation by neonatal DCs. Human adult Vγ9Vδ2 T cells...
5.
Vermijlen D, Brouwer M, Donner C, Liesnard C, Tackoen M, Van Rysselberge M, et al.
J Exp Med
. 2010 Apr;
207(4):807-21.
PMID: 20368575
The fetus and infant are highly susceptible to viral infections. Several viruses, including human cytomegalovirus (CMV), cause more severe disease in early life compared with later life. It is generally...
6.
Lievens B, Brouwer M, Vanachter A, Levesque C, Cammue B, Thomma B
Environ Microbiol
. 2005 Oct;
7(11):1698-710.
PMID: 16232285
Detection, identification and quantification of plant pathogens are the cornerstones of preventive plant disease management. To detect multiple pathogens in a single assay, DNA array technology currently is the most...
7.
Pollakis G, Abebe A, Kliphuis A, Chalaby M, Bakker M, Mengistu Y, et al.
J Virol
. 2004 Mar;
78(6):2841-52.
PMID: 14990703
Individuals infected with human immunodeficiency virus type 1 (HIV-1) subtype C infrequently harbour X4 viruses. We studied R5 and X4 biological clones generated from HIV-1 subtype C-infected individuals. All subtype...
8.
Brouwer M, Lievens B, Van Hemelrijck W, Van den Ackerveken G, Cammue B, Thomma B
FEMS Microbiol Lett
. 2003 Nov;
228(2):241-8.
PMID: 14638430
An accurate monitoring of disease progression is important to evaluate disease susceptibility phenotypes. Over the years, Arabidopsis thaliana has become the model species to serve as a host in plant-pathogen...
9.
Lievens B, Brouwer M, Vanachter A, Levesque C, Cammue B, Thomma B
FEMS Microbiol Lett
. 2003 Jun;
223(1):113-22.
PMID: 12799009
Fusarium wilt, caused by Fusarium oxysporum f. sp. lycopersici, and Verticillium wilt, caused by either Verticillium albo-atrum or Verticillium dahliae, are devastating diseases of tomato (Lycopersicon esculentum) found worldwide. Monitoring...
10.
Tierens K, Thomma B, Bari R, Garmier M, Eggermont K, Brouwer M, et al.
Plant J
. 2002 Feb;
29(2):131-40.
PMID: 11862946
An Arabidopsis thaliana mutant, esa1, that shows enhanced susceptibility to the necrotrophic pathogens Alternaria brassicicola, Botrytis cinerea and Plectosphaerella cucumerina, but has wild-type levels of resistance to the biotrophic pathogens...