Margherita Norelli
Overview
Explore the profile of Margherita Norelli including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
979
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0
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Recent Articles
1.
Biavasco R, Lettera E, Giannetti K, Gilioli D, Beretta S, Conti A, et al.
Nat Commun
. 2021 Jul;
12(1):4559.
PMID: 34315896
Activating mutations in the BRAF-MAPK pathway have been reported in histiocytoses, hematological inflammatory neoplasms characterized by multi-organ dissemination of pro-inflammatory myeloid cells. Here, we generate a humanized mouse model of...
2.
Escobar G, Barbarossa L, Barbiera G, Norelli M, Genua M, Ranghetti A, et al.
Nat Commun
. 2018 Jul;
9(1):2896.
PMID: 30042420
Immunotherapy is emerging as a new pillar of cancer treatment with potential to cure. However, many patients still fail to respond to these therapies. Among the underlying factors, an immunosuppressive...
3.
Norelli M, Camisa B, Barbiera G, Falcone L, Purevdorj A, Genua M, et al.
Nat Med
. 2018 May;
24(6):739-748.
PMID: 29808007
In the clinic, chimeric antigen receptor-modified T (CAR T) cell therapy is frequently associated with life-threatening cytokine-release syndrome (CRS) and neurotoxicity. Understanding the nature of these pathologies and developing treatments...
4.
Casucci M, Falcone L, Camisa B, Norelli M, Porcellini S, Stornaiuolo A, et al.
Front Immunol
. 2018 Apr;
9:507.
PMID: 29619024
Chimeric antigen receptor (CAR)-T cell immunotherapy is at the forefront of innovative cancer therapeutics. However, lack of standardization of cellular products within the same clinical trial and lack of harmonization...
5.
Norelli M, Camisa B, Bondanza A
Methods Mol Biol
. 2016 Apr;
1393:127-32.
PMID: 27033222
Hematopoietic stem cell transplantation (HSCT) from an allogeneic donor is an effective form of cancer immunotherapy, especially for acute leukemias. HSCT is however frequently complicated by the occurrence of graft-versus-host...
6.
Casucci M, di Robilant B, Falcone L, Camisa B, Norelli M, Genovese P, et al.
Blood
. 2013 Sep;
122(20):3461-72.
PMID: 24016461
Genetically targeted T cells promise to solve the feasibility and efficacy hurdles of adoptive T-cell therapy for cancer. Selecting a target expressed in multiple-tumor types and that is required for...