Margarete Manhaes Trachez
Overview
Explore the profile of Margarete Manhaes Trachez including associated specialties, affiliations and a list of published articles.
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7
Citations
28
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Recent Articles
1.
Sudo S, Montagnoli T, Dematte B, Santos A, Trachez M, Gubert F, et al.
J Pain Res
. 2025 Jan;
18():127-136.
PMID: 39816206
Introduction: Diabetes mellitus (DM) has become a public health problem, which is associated with high morbidity and mortality, due to the chronic complications, such as diabetic neuropathy. Current recommendations for...
2.
Vieira M, Monte F, Dematte B, Montagnoli T, Montes G, Silva J, et al.
J Pain Res
. 2021 Apr;
14:857-866.
PMID: 33833563
Introduction: New therapeutic alternatives for pain relief include the use of phosphodiesterase-5 (PDE5) inhibitors, which could prevent the transmission of painful stimuli by neuron hyperpolarization via nitric oxide (NO)/cyclic 3',5'-guanosine...
3.
Costa G, Montagnoli T, Silva J, Nogueira de Alencar A, Gamba L, Alves B, et al.
Drug Des Devel Ther
. 2020 Sep;
14:3337-3350.
PMID: 32884238
Introduction: Diabetic obese patients are susceptible to the development of cardiovascular disease, including hypertension and cardiac dysfunction culminating in diabetic cardiomyopathy (DC), which represents a life-threatening health problem with increased...
4.
Zapata-Sudo G, da Costa Nunes I, Araujo J, Silva J, Trachez M, da Silva T, et al.
Drug Des Devel Ther
. 2016 Sep;
10:2869-2879.
PMID: 27672310
Neuropathy is a serious complication of diabetes that has a significant socioeconomic impact, since it frequently demands high levels of health care consumption and compromises labor productivity. Recently, LASSBio-1471 (3)...
5.
Sudo R, Bonfa L, Trachez M, Debom R, Rizzi M, Zapata-Sudo G
Rev Bras Anestesiol
. 2010 Sep;
60(5):475-83.
PMID: 20863928
Background And Objectives: The clinical use of a lipid propofol formulation causes pain during injection, allergic reactions, and bacterial growth. Propofol has been reformulated in different non-lipid presentations to reduce...
6.
do Carmo P, Zapata-Sudo G, Trachez M, das Gracas Fernandes Sales M, Sudo R
Fundam Clin Pharmacol
. 2009 Nov;
24(4):491-500.
PMID: 19889027
We investigated the toxicity of azumolene (Az), a more water-soluble compound than dantrolene, after 14 days of intraperitoneal (i.p.) administration in rats at doses of 1, 2.5 or 10 mg/kg/day....
7.
Sudo R, do Carmo P, Trachez M, Zapata-Sudo G
Basic Clin Pharmacol Toxicol
. 2007 Dec;
102(3):308-16.
PMID: 18047479
Malignant hyperthermia is a pharmacogenetic disease of skeletal muscle in which a life-threatening, hypermetabolic syndrome is induced by exposure of susceptible patients to halogenated general anaesthetics and/or succinylcholine. Dantrolene sodium,...
8.
Raimundo J, Sudo R, Pontes L, Antunes F, Trachez M, Zapata-Sudo G
Eur J Pharmacol
. 2005 Dec;
530(1-2):117-23.
PMID: 16371227
Tramadol ((+/-)-tramadol) is an analgesic agent formulated as a racemic mixture (1:1) of (-)- and (+)-tramadol, which differ in their potency to bind to mu-opioid receptors and to inhibit monoamine-reuptake....