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Margaret OMalley

Explore the profile of Margaret OMalley including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 314
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Recent Articles
11.
Yoon J, Mehta N, Burke C, Augustin T, OMalley M, LaGuardia L, et al.
Ann Surg . 2019 Dec; 274(6):e1071-e1077. PMID: 31850977
Objective: To evaluate the prevalence, natural history, and severity of polyposis of the duodenal bulb and jejunum after duodenectomy in patients with FAP. Summary Of Background Data: Advanced duodenal polyposis...
12.
Wood E, Church J, OMalley M, LaGuardia L, Heald B, Burke C, et al.
Dis Colon Rectum . 2019 Sep; 62(10):1204-1211. PMID: 31490829
Background: Almost all patients with familial adenomatous polyposis undergo abdominal surgery with a risk of disease and surgery-related complications. This, the familial nature of the syndrome, and its wide-ranging manifestations...
13.
Thiruvengadam S, OMalley M, LaGuardia L, Lopez R, Wang Z, Shadrach B, et al.
Clin Transl Gastroenterol . 2019 Jun; 10(6):e00053. PMID: 31211760
Objectives: Duodenal cancer in familial adenomatous polyposis (FAP) arises from adenomas. Differentially expressed genes (DEGs) in the duodenal adenoma-carcinoma pathway have been identified in murine FAP models, but similar data...
14.
Leone P, Mankaney G, Sarvapelli S, Abushamma S, Lopez R, Cruise M, et al.
Gastrointest Endosc . 2019 Jan; 89(5):961-968. PMID: 30597145
Background And Aims: Gastric cancer (GC) is a newly described cancer risk in Western patients with familial adenomatous polyposis (FAP). Little is known about clinical, endoscopic, and pathologic features associated...
15.
Sarvepalli S, Burke C, Monachese M, Lopez R, Leach B, LaGuardia L, et al.
Am J Gastroenterol . 2018 Oct; 113(12):1881-1890. PMID: 30333551
Introduction: The timing of prophylactic colorectal surgery in patients with familial adenomatous polyposis (FAP) is based on the immediacy of the colorectal cancer risk. The ability to predict the need...
16.
Thiruvengadam S, Lopez R, OMalley M, LaGuardia L, Church J, Kalady M, et al.
Gastrointest Endosc . 2018 Aug; 89(2):345-354.e2. PMID: 30081000
Background And Aims: The greatest known risk factor for duodenal cancer in familial adenomatous polyposis (FAP) is Spigelman stage (SS) IV duodenal polyposis. Endoscopic surveillance is recommended in FAP patients...
17.
Monachese M, Mankaney G, Lopez R, OMalley M, LaGuardia L, Kalady M, et al.
Fam Cancer . 2018 Jul; 18(1):75-82. PMID: 30003385
Familial adenomatous polyposis (FAP) is a hereditary cancer syndrome associated with a substantial lifetime risk for colorectal cancer. The leading extra-colonic causes of cancer in FAP include duodenal and thyroid...
18.
Sarvepalli S, Burke C, Monachese M, Leach B, LaGuardia L, OMalley M, et al.
Gastrointest Endosc . 2018 Jun; 88(4):726-733. PMID: 29864420
Background And Aims: Proctocolectomy prevents colorectal cancer in familial adenomatous polyposis (FAP). Colorectal polyp progression is one of the indications for surgery. No data exist regarding the natural history of...
19.
Mankaney G, Leone P, Cruise M, LaGuardia L, OMalley M, Bhatt A, et al.
Fam Cancer . 2017 Feb; 16(3):371-376. PMID: 28185118
The highest cancer risks in familial adenomatous polyposis (FAP) include colorectal, duodenal, and thyroid for which surveillance is recommended. Nearly all patients with FAP have gastric fundic gland polyposis (FGP),...
20.
Plesec T, Brown K, Allen C, Burke C, Church J, Kalady M, et al.
Hum Pathol . 2016 Dec; 60:75-81. PMID: 27984123
Since first characterized in 1997, patients with hereditary mixed polyposis syndrome (HMPS) have been difficult to identify because of lack of well-established diagnostic criteria. Recently, HMPS was found to be...