Margaret C Cummings
Overview
Explore the profile of Margaret C Cummings including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
692
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0
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Recent Articles
1.
Kim W, Cummings M, Lakhani S
Expert Rev Anticancer Ther
. 2020 Mar;
20(3):205-219.
PMID: 32174198
: Breast cancer is a heterogeneous disease, at morphological, molecular, and clinical levels and this has significant implications for the diagnosis and management of the disease. The introduction of breast...
2.
Kutasovic J, McCart Reed A, Males R, Sim S, Saunus J, Dalley A, et al.
J Pathol Clin Res
. 2018 Sep;
5(1):25-39.
PMID: 30246500
Breast cancer metastasis to gynaecological organs is an understudied pattern of tumour spread. We explored clinico-pathological and molecular features of these metastases to better understand whether this pattern of dissemination...
3.
McCart Reed A, Kutasovic J, Nones K, Saunus J, Da Silva L, Newell F, et al.
J Pathol
. 2018 Jan;
244(4):460-468.
PMID: 29344954
Mixed ductal-lobular carcinomas (MDLs) show both ductal and lobular morphology, and constitute an archetypal example of intratumoural morphological heterogeneity. The mechanisms underlying the coexistence of these different morphological entities are...
4.
Hendry S, Pang J, Byrne D, Lakhani S, Cummings M, Campbell I, et al.
Clin Cancer Res
. 2017 Jun;
23(17):5210-5217.
PMID: 28611201
The immune microenvironment of breast ductal carcinoma (DCIS) has yet to be fully explored, and the relationship of immune cells to genetic features of DCIS is unknown. We quantified tumor...
5.
Pang J, Savas P, Fellowes A, Arnau G, Kader T, Vedururu R, et al.
Mod Pathol
. 2017 Mar;
30(7):952-963.
PMID: 28338653
The spectrum of genomic alterations in ductal carcinoma in situ (DCIS) is relatively unexplored, but is likely to provide useful insights into its biology, its progression to invasive carcinoma and...
6.
Shield P, Frost F, Finnimore J, Wright R, Cummings M
Cancer Cytopathol
. 2017 Feb;
125(5):349-361.
PMID: 28241108
Background: The Royal College of Pathologists of Australasia Cytopathology Quality Assurance Program has operated an external quality assurance program in nongynecologic cytopathology since 1993. Glass slide preparations of a wide...
7.
Packer L, Geng X, Bonazzi V, Ju R, Mahon C, Cummings M, et al.
Mol Cancer Ther
. 2017 Jan;
16(4):637-648.
PMID: 28119489
Improved therapeutic approaches are needed for the treatment of recurrent and metastatic endometrial cancer. Endometrial cancers display hyperactivation of the MAPK and PI3K pathways, the result of somatic aberrations in...
8.
Field S, Uyttenhove C, Stroobant V, Cheou P, Donckers D, Coutelier J, et al.
Int J Cancer
. 2015 Dec;
138(8):1959-70.
PMID: 26619948
Periostin (POSTN), a secreted homodimeric protein that binds integrins αvβ3, αvβ5, and α6β4, was originally found to be expressed in fetal tissues and in the adult upon injury particularly bone...
9.
Saunus J, Quinn M, Patch A, Pearson J, Bailey P, Nones K, et al.
J Pathol
. 2015 Jul;
237(3):363-78.
PMID: 26172396
Treatment options for patients with brain metastases (BMs) have limited efficacy and the mortality rate is virtually 100%. Targeted therapy is critically under-utilized, and our understanding of mechanisms underpinning metastatic...
10.
Antill Y, Dowty J, Win A, Thompson T, Walsh M, Cummings M, et al.
Int J Cancer
. 2015 Jun;
137(11):2757-61.
PMID: 26077226
Carriers of germline mutations in DNA mismatch repair (MMR) genes are at increased risk of several cancers including colorectal and gynecologic cancers (Lynch syndrome). There is no substantial evidence that...