Marcus Davidsson
Overview
Explore the profile of Marcus Davidsson including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
239
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0
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Recent Articles
1.
Sandoval I, Kelley C, Bernal-Conde L, Steece-Collier K, Marmion D, Davidsson M, et al.
Mol Ther Nucleic Acids
. 2024 Oct;
35(4):102332.
PMID: 39445231
Adeno-associated virus (AAV)-based gene therapy has enjoyed great successes over the past decade, with Food and Drug Administration-approved therapeutics and a robust clinical pipeline. Nonetheless, barriers to successful translation remain....
2.
Storm P, Zhang Y, Nilsson F, Fiorenzano A, Krausse N, Akerblom M, et al.
Sci Adv
. 2024 Oct;
10(42):eadn3057.
PMID: 39423273
Stem cell therapies for Parkinson's disease are at an exciting time of development, and several clinical trials have recently been initiated. Human pluripotent stem cells are differentiated into transplantable dopamine...
3.
Giacomoni J, Akerblom M, Habekost M, Fiorenzano A, Kajtez J, Davidsson M, et al.
Front Neurosci
. 2024 Aug;
18:1435212.
PMID: 39193523
Direct neural conversion of endogenous non-neuronal cells, such as resident glia, into therapeutic neurons has emerged as a promising strategy for brain repair, aiming to restore lost or damaged neurons....
4.
Avallone M, Pardo J, Mergiya T, Rajova J, Rasanen A, Davidsson M, et al.
Front Mol Neurosci
. 2023 Jul;
16:1140785.
PMID: 37415832
The activity-regulated cytoskeleton-associated (Arc) protein is essential for synaptic plasticity and memory formation. The Arc gene, which contains remnants of a structural GAG retrotransposon sequence, produces a protein that self-assembles...
5.
Rajova J, Davidsson M, Avallone M, Hartnor M, Aldrin-Kirk P, Cardoso T, et al.
Mol Ther Methods Clin Dev
. 2023 May;
29:381-394.
PMID: 37251982
Cell therapy for Parkinson's disease has experienced substantial growth in the past decades with several ongoing clinical trials. Despite increasing refinement of differentiation protocols and standardization of the transplanted neural...
6.
Anwer D, Gubinelli F, Kurt Y, Sarauskyte L, Jacobs F, Venuti C, et al.
PLoS One
. 2023 May;
18(5):e0284480.
PMID: 37126506
Microglial cells are brain-specific macrophages that swiftly react to disruptive events in the brain. Microglial activation leads to specific modifications, including proliferation, morphological changes, migration to the site of insult,...
7.
Quintino L, Gubinelli F, Sarauskyte L, Arvidsson E, Davidsson M, Lundberg C, et al.
J Neurosci Methods
. 2022 Jun;
378:109640.
PMID: 35690332
Background: The development of axonal pathology is a key characteristic of many neurodegenerative disease such as Parkinson's disease and Alzheimer's disease. With advanced disease progression, affected axons do display several...
8.
Negrini M, Tomasello G, Davidsson M, Fenyi A, Adant C, Hauser S, et al.
J Parkinsons Dis
. 2022 Feb;
12(4):1133-1153.
PMID: 35213388
Background: Preclinical rodent models for Parkinson's disease (PD) based on viral human alpha-synuclein (h-αSyn) overexpression recapitulate some of the pathological hallmarks as it presents in humans, such as progressive cell...
9.
Aldrin-Kirk P, Akerblom M, Cardoso T, Nolbrant S, Adler A, Liu X, et al.
Stem Cell Reports
. 2021 Dec;
17(1):159-172.
PMID: 34971563
Transplantation in Parkinson's disease using human embryonic stem cell (hESC)-derived dopaminergic (DA) neurons is a promising future treatment option. However, many of the mechanisms that govern their differentiation, maturation, and...
10.
Bjorklund T, Davidsson M
J Parkinsons Dis
. 2021 Aug;
11(s2):S209-S217.
PMID: 34366370
Recent technological and conceptual advances have resulted in a plethora of exciting novel engineered adeno associated viral (AAV) vector variants. They all have unique characteristics and abilities. This review summarizes...