Marco Moracci
Overview
Explore the profile of Marco Moracci including associated specialties, affiliations and a list of published articles.
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Articles
67
Citations
842
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Recent Articles
1.
Iacono R, Paragliola F, Strazzulli A, Moracci M
J Enzyme Inhib Med Chem
. 2025 Feb;
40(1):2468859.
PMID: 39995088
GH31 glycosidases are widespread across organisms, but remarkably, less than 1% of them have been biochemically characterised to date. Among them, human lysosomal acid α-glucosidase (GAA) stands out due to...
2.
Shaikh-Ibrahim A, Curci N, De Lise F, Sacco O, Di Fenza M, Castaldi S, et al.
Biotechnol Biofuels Bioprod
. 2025 Jan;
18(1):2.
PMID: 39773291
Background: Spent coffee grounds (SCG) are the most abundant waste byproducts generated from coffee beverage production worldwide. Typically, these grounds are seen as waste and end up in landfills. However,...
3.
Ercolano C, Iacono R, Cafaro V, Pizzo E, Giovannelli D, Feuerriegel G, et al.
Int J Mol Sci
. 2024 Aug;
25(15).
PMID: 39125688
Polyethylene terephthalate (PET) degradation by enzymatic hydrolysis is significant for addressing plastic pollution and fostering sustainable waste management practices. Identifying thermophilic and thermostable PET hydrolases is particularly crucial for industrial...
4.
Cinti S, Singh S, Covone G, Tonietti L, Ricciardelli A, Cordone A, et al.
Front Microbiol
. 2023 Sep;
14:1215529.
PMID: 37664111
The space race is entering a new era of exploration, in which the number of robotic and human missions to various places in our solar system is rapidly increasing. Despite...
5.
Curci N, Iacono R, Raventos Segura D, Cillo M, Cobucci-Ponzano B, Strazzulli A, et al.
N Biotechnol
. 2023 Aug;
77:130-138.
PMID: 37643666
Glycoside hydrolases (GHs) have been employed for industrial and biotechnological purposes and often play an important role in new applications. The red blood cell (RBC) antigen system depends on the...
6.
Iacono R, De Lise F, Moracci M, Cobucci-Ponzano B, Strazzulli A
Essays Biochem
. 2023 Jun;
67(4):731-751.
PMID: 37341134
(Hyper)thermophilic archaeal glycosidases are enzymes that catalyze the hydrolysis of glycosidic bonds to break down complex sugars and polysaccharides at high temperatures. These enzymes have an unique structure that allows...
7.
De Lise F, Iacono R, Moracci M, Strazzulli A, Cobucci-Ponzano B
Biomolecules
. 2023 Jan;
13(1).
PMID: 36671499
Archaea represents the third domain of life, displaying a closer relationship with eukaryotes than bacteria. These microorganisms are valuable model systems for molecular biology and biotechnology. In fact, nowadays, methanogens,...
8.
Iacono R, Strazzulli A, Giglio R, Bitetti F, Cobucci-Ponzano B, Moracci M
Int J Mol Sci
. 2022 Sep;
23(18).
PMID: 36142415
The increasing interest for environmentally friendly technologies is driving the transition from fossil-based economy to bioeconomy. A key enabler for circular bioeconomy is to valorize renewable biomasses as feedstock to...
9.
Tarallo A, Damiano C, Strollo S, Minopoli N, Indrieri A, Polishchuk E, et al.
EMBO Mol Med
. 2021 Oct;
13(11):e14434.
PMID: 34606154
Pompe disease is a metabolic myopathy due to acid alpha-glucosidase deficiency. In addition to glycogen storage, secondary dysregulation of cellular functions, such as autophagy and oxidative stress, contributes to the...
10.
Iacono R, Minopoli N, Ferrara M, Tarallo A, Damiano C, Porto C, et al.
J Enzyme Inhib Med Chem
. 2021 Sep;
36(1):2068-2079.
PMID: 34565280
Pompe disease is an inherited metabolic disorder due to the deficiency of the lysosomal acid -glucosidase (GAA). The only approved treatment is enzyme replacement therapy with the recombinant enzyme (rhGAA)....