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Marco Gerling

Explore the profile of Marco Gerling including associated specialties, affiliations and a list of published articles. Areas
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Citations 560
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Recent Articles
11.
Andrews N, Serviss J, Geyer N, Andersson A, Dzwonkowska E, Sutevski I, et al.
Nat Methods . 2021 Jul; 18(8):912-920. PMID: 34253926
Cellular identity in complex multicellular organisms is determined in part by the physical organization of cells. However, large-scale investigation of the cellular interactome remains technically challenging. Here we develop cell...
12.
Bergstrom A, Gerling M, Van Hul N, Moro C, Rozell B, Toftgard R, et al.
Transgenic Res . 2021 Jun; 30(5):701-707. PMID: 34117597
Chronic cholestatic liver diseases including primary sclerosing cholangitis (PSC) present a complex spectrum with regards to the cause, age of manifestation and histopathological features. Current treatment options are severely limited...
13.
Geyer N, Gerling M
Int J Mol Sci . 2021 Jan; 22(3). PMID: 33498528
Hedgehog (Hh) signaling regulates intestinal development and homeostasis. The role of Hh signaling in cancer has been studied for many years; however, its role in colorectal cancer (CRC) remains controversial....
14.
Sun X, Are A, Annusver K, Sivan U, Jacob T, Dalessandri T, et al.
Elife . 2020 Mar; 9. PMID: 32178760
Hair follicle (HF) development is orchestrated by coordinated signals from adjacent epithelial and mesenchymal cells. In humans this process only occurs during embryogenesis and viable strategies to induce new HFs...
15.
Kordes M, Gerling M
ESMO Open . 2019 Dec; 4(6):e000607. PMID: 31803505
Background: Chemotherapy-induced diarrhoea (CID) is a common side effect of cancer treatment. While cytotoxic agents are the main cause of CID, targeted drugs, immunotherapy and radiotherapy can also cause diarrhoea....
16.
Latacz E, Caspani E, Barnhill R, Lugassy C, Verhoef C, Grunhagen D, et al.
Angiogenesis . 2019 Oct; 23(1):43-54. PMID: 31655928
Cancer cells can use existing blood vessels to acquire a vasculature. This process is termed 'vessel co-option'. Vessel co-option is an alternative to the growth of new blood vessels, or...
17.
Rohwer N, Jumpertz S, Erdem M, Egners A, Warzecha K, Fragoulis A, et al.
Oncogene . 2019 May; 38(28):5670-5685. PMID: 31043706
The hypoxia-inducible transcription factor HIF-1 is appreciated as a promising target for cancer therapy. However, conditional deletion of HIF-1 and HIF-1 target genes in cells of the tumor microenvironment can...
18.
Friedrich M, Gerbeth L, Gerling M, Rosenthal R, Steiger K, Weidinger C, et al.
Mucosal Immunol . 2019 Jan; 12(3):656-667. PMID: 30674988
Intact epithelial barrier function is pivotal for maintaining intestinal homeostasis. Current therapeutic developments aim at restoring the epithelial barrier in inflammatory bowel disease. Histone deacetylase (HDAC) inhibitors are known to...
19.
Moro C, Bozoky B, Gerling M
BMJ Open Gastroenterol . 2018 Aug; 5(1):e000217. PMID: 30073092
Background: Colorectal cancer liver metastases (CRLM) grow in distinct histological patterns that have been associated with outcome after surgical resection. We conducted a systematic review to evaluate the frequency of...
20.
Hoelzl M, Heby-Henricson K, Gerling M, Dias J, Kuiper R, Trunkle C, et al.
Dev Biol . 2017 Jul; 429(1):132-146. PMID: 28688895
Suppressor of Fused (SUFU) is an essential negative regulator of the Hedgehog (HH) pathway and involved in GLI transcription factor regulation. Due to early embryonic lethality of Sufu mice, investigations...