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Marco Crosariol

Explore the profile of Marco Crosariol including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 451
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Recent Articles
1.
Jiao X, Di Sante G, Casimiro M, Tantos A, Ashton A, Li Z, et al.
Oncogenesis . 2024 Jan; 13(1):4. PMID: 38191593
The essential G-cyclin, CCND1, is frequently overexpressed in cancer, contributing to tumorigenesis by driving cell-cycle progression. D-type cyclins are rate-limiting regulators of G-S progression in mammalian cells via their ability...
2.
Elkouby L, Armour S, Toso R, DiPietro M, Davidson R, Nguyen G, et al.
Mol Ther Methods Clin Dev . 2022 Jan; 24:20-29. PMID: 34977269
Extensive clinical data from liver-mediated gene therapy trials have shown that dose-dependent immune responses against the vector capsid may impair or even preclude transgene expression if not managed successfully with...
3.
Costa-Verdera H, Collaud F, Riling C, Sellier P, Nordin J, Preston G, et al.
Nat Commun . 2021 Nov; 12(1):6393. PMID: 34737297
Pompe disease (PD) is a severe neuromuscular disorder caused by deficiency of the lysosomal enzyme acid alpha-glucosidase (GAA). PD is currently treated with enzyme replacement therapy (ERT) with intravenous infusions...
4.
Tycko J, Adam V, Crosariol M, Ohlstein J, Sanmiguel J, Tretiakova A, et al.
Hum Gene Ther . 2021 Aug; 32(23-24):1450-1456. PMID: 34415793
Infants and older adults are especially vulnerable to infection by respiratory syncytial virus (RSV), which can cause significant illness and irreparable damage to the lower respiratory tract and for which...
5.
Limberis M, Tretiakova A, Nambiar K, Wong G, Racine T, Crosariol M, et al.
J Infect Dis . 2016 Sep; 214(12):1975-1979. PMID: 27683818
Adeno-associated viral vectors can be used as a platform for delivering biological countermeasures against pandemic and biological threats. We show that vector delivery of two antibody components of the ZMapp...
6.
Casimiro M, Di Sante G, Ju X, Li Z, Chen K, Crosariol M, et al.
Cancer Res . 2015 Nov; 76(2):329-38. PMID: 26582866
Therapy resistance and poor outcome in prostate cancer is associated with increased expression of cyclin D1. Androgens promote DNA double-strand break repair to reduce DNA damage, and cyclin D1 was...
7.
Casimiro M, Di Sante G, Crosariol M, Loro E, Dampier W, Ertel A, et al.
Oncotarget . 2015 May; 6(11):8525-38. PMID: 25940700
Cyclin D1 is an important molecular driver of human breast cancer but better understanding of its oncogenic mechanisms is needed, especially to enhance efforts in targeted therapeutics. Currently, pharmaceutical initiatives...
8.
Adam V, Crosariol M, Kumar S, Ge M, Czack S, Roy S, et al.
Clin Vaccine Immunol . 2014 Sep; 21(11):1528-33. PMID: 25209558
Influenza causes serious and sometimes fatal disease in individuals at risk due to advanced age or immunodeficiencies. Despite progress in the development of seasonal influenza vaccines, vaccine efficacy in elderly...
9.
Ju X, Casimiro M, Gormley M, Meng H, Jiao X, Katiyar S, et al.
Cancer Res . 2013 Nov; 74(2):508-19. PMID: 24282282
Improved clinical management of prostate cancer has been impeded by an inadequate understanding of molecular genetic elements governing tumor progression. Gene signatures have provided improved prognostic indicators of human prostate...
10.
Casimiro M, Crosariol M, Loro E, Li Z, Pestell R
Genes Cancer . 2013 May; 3(11-12):649-57. PMID: 23634253
Cyclin D1 overexpression is found in more than 50% of human breast cancers and causes mammary cancer in transgenic mice. Dysregulation of cyclin D1 gene expression or function contributes to...