Marcin Ufnal
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Explore the profile of Marcin Ufnal including associated specialties, affiliations and a list of published articles.
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96
Citations
1626
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Recent Articles
1.
Gasecka A, Gniot M, Rajewska B, Dykacz W, Kisielewska W, Blazejowska E, et al.
Cardiol J
. 2025 Mar;
PMID: 40062926
Background: Intestinal microbial metabolites, such as trimethylamine-N-oxide (TMAO) and indoxyl sulfate (IS), have been suggested as markers for the progression of aortic stenosis (AS). However, the impact of transcatheter aortic...
2.
Ufnal M, Connolly K, Millegard M, Surkova E, Guazzi M, Bonderman D, et al.
ESC Heart Fail
. 2025 Jan;
PMID: 39829393
Aims: Despite receiving guideline-directed medical heart failure (HF) therapy, patients with pulmonary hypertension associated with left heart disease (PH-LHD) experience higher mortality and hospitalization rates than the general HF population....
3.
Jaworska K, Kopacz W, Koper M, Ufnal M
Int J Mol Sci
. 2024 Dec;
25(23).
PMID: 39684223
Biomarkers play a crucial role in various stages of disease management, including screening, diagnosis, prediction, prognosis, treatment, and safety monitoring. Although they are powerful tools in disease diagnosis, management, and...
4.
Szudzik M, Hutsch T, Chabowski D, Zajdel M, Ufnal M
Sci Rep
. 2024 Oct;
14(1):22796.
PMID: 39354056
Excessive caloric intake and obesity due to high-fat (HFD) and high-disaccharide (HDD) diets have been recognized as major contributing factors to dyslipidemia and metabolic dysfunction-associated steatotic liver disease (MASLD). However,...
5.
Connolly K, George R, Omar S, Matsson E, Astrand M, Althage M, et al.
J Am Heart Assoc
. 2024 Jul;
13(15):e034067.
PMID: 39056338
Background: Heart failure mortality remains high despite recent progress in pharmacological treatment. AZD3427 is a selective long-acting analog of relaxin, a vasodilatory hormone with antifibrotic effects. We assessed the safety,...
6.
Gawrys-Kopczynska M, Szudzik M, Samborowska E, Konop M, Chabowski D, Onyszkiewicz M, et al.
Front Physiol
. 2024 Apr;
15:1340166.
PMID: 38681141
Flavin monooxygenases (FMOs) are enzymes responsible for the oxidation of a broad spectrum of exogenous and endogenous amines. There is increasing evidence that trimethylamine (TMA), a compound produced by gut...
7.
Maksymiuk K, Szudzik M, Samborowska E, Chabowski D, Konop M, Ufnal M
PLoS One
. 2024 Jan;
19(1):e0297474.
PMID: 38266015
Introduction: Increased plasma trimethylamine oxide (TMAO) is observed in cardiovascular and metabolic diseases, originating from the gut microbiota product, trimethylamine (TMA), via flavin-containing monooxygenases (FMOs)-dependent oxidation. Numerous studies have investigated...
8.
Nowinski A, Chabowski D, Giebultowicz J, Aleksandrowicz M, Ufnal M
Nutrients
. 2024 Jan;
16(1).
PMID: 38201862
Background: Deoxycholic acid (DCA) is a secondary bile acid produced by gut bacteria. Elevated serum concentrations of DCA are observed in cardiovascular disease (CVD). We hypothesized that DCA might influence...
9.
Mogilnicka I, Jaworska K, Koper M, Maksymiuk K, Szudzik M, Radkiewicz M, et al.
PLoS One
. 2024 Jan;
19(1):e0294926.
PMID: 38166023
Hypertension leads to water-electrolyte disturbances and end-organ damage. Betaine is an osmolyte protecting cells against electrolyte imbalance and osmotic stress, particularly in the kidneys. This study aimed to evaluate tissue...
10.
Tomasova L, Maksymiuk K, Chabowski D, Samborowska E, Ufnal M
Discov Med
. 2023 Aug;
35(177):492-502.
PMID: 37553303
Background: Osmolytes are naturally occurring compounds that protect cells from osmotic stress in high-osmolarity tissues, such as the kidney medulla. Some amino acids, including taurine, betaine, glycine, alanine, and sarcosine,...