Marcel Seibert
Overview
Explore the profile of Marcel Seibert including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
94
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Recent Articles
1.
Seibert M, Koschade S, Stolp V, Haupl B, Wempe F, Serve H, et al.
Cancers (Basel)
. 2023 Dec;
15(23).
PMID: 38067212
Multiple myeloma (MM) is a malignant plasma cell disorder in which the MYC oncogene is frequently dysregulated. Due to its central role, MYC has been proposed as a drug target;...
2.
Alshamleh I, Kurrle N, Makowka P, Bhayadia R, Kumar R, Susser S, et al.
Leukemia
. 2023 Nov;
37(12):2367-2382.
PMID: 37935978
High metabolic flexibility is pivotal for the persistence and therapy resistance of acute myeloid leukemia (AML). In 20-30% of AML patients, activating mutations of FLT3, specifically FLT3-ITD, are key therapeutic...
3.
Seibert M, Kurrle N, Stolp V, Nurnberger H, Tzschentke S, Borner L, et al.
MethodsX
. 2022 Nov;
9:101929.
PMID: 36444289
Endogenous protein tagging, in contrast to exogenous overexpression of tagged proteins, allows to characterize specific protein functions under defined physiological or pathophysiological conditions without the influence of non-physiological protein levels....
4.
Clees A, Stolp V, Haupl B, Fuhrmann D, Wempe F, Seibert M, et al.
Cells
. 2022 Jan;
11(2).
PMID: 35053409
Multiple myeloma (MM) is the second most common hematologic malignancy, which is characterized by clonal proliferation of neoplastic plasma cells in the bone marrow. This microenvironment is characterized by low...
5.
Nimbarte V, Wirmer-Bartoschek J, Gande S, Alshamleh I, Seibert M, Nasiri H, et al.
ChemMedChem
. 2021 Jan;
16(10):1667-1679.
PMID: 33508167
Lead-optimization strategies for compounds targeting c-Myc G-quadruplex (G4) DNA are being pursued to develop anticancer drugs. Here, we investigate the structure-activity- relationship (SAR) of a newly synthesized series of molecules...
6.
Seibert M, Kurrle N, Schnutgen F, Serve H
Matrix Biol
. 2021 Jan;
100-101:65-83.
PMID: 33429026
Autophagy is the highly conserved catabolic process, which enables the survival of a cell under unfavorable environmental conditions. In a constantly changing environment, cells must be capable of dynamically oscillating...
7.
Kreitz J, Schonfeld C, Seibert M, Stolp V, Alshamleh I, Oellerich T, et al.
Cells
. 2019 Aug;
8(8).
PMID: 31370337
Acute myeloid leukemia (AML) is one of the most common and life-threatening leukemias. A highly diverse and flexible metabolism contributes to the aggressiveness of the disease that is still difficult...