Marcel P Stoop
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Explore the profile of Marcel P Stoop including associated specialties, affiliations and a list of published articles.
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24
Citations
376
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Recent Articles
1.
Bruijstens A, Stingl C, Guzel C, Stoop M, Wong Y, van Pelt E, et al.
Mult Scler
. 2022 Sep;
29(1):52-62.
PMID: 36154753
Background: Pediatric-onset multiple sclerosis (POMS) represents the earliest stage of disease pathogenesis. Investigating the cerebrospinal fluid (CSF) proteome in POMS may provide novel insights into early MS processes. Objective: To...
2.
van der Ende E, Meeter L, Stingl C, van Rooij J, Stoop M, Nijholt D, et al.
Ann Clin Transl Neurol
. 2019 Apr;
6(4):698-707.
PMID: 31019994
Objective: To identify novel CSF biomarkers in -associated frontotemporal dementia (FTD) by proteomics using mass spectrometry (MS). Methods: Unbiased MS was applied to CSF samples from 19 presymptomatic and 9...
3.
Ongay S, Langelaar-Makkinje M, Stoop M, Liu N, Overkleeft H, Luider T, et al.
Chembiochem
. 2018 Jan;
19(7):736-743.
PMID: 29356267
Formaldehyde fixation is widely used for long-term maintenance of tissue. However, due to formaldehyde-induced crosslinks, fixed tissue proteins are difficult to extract, which hampers mass spectrometry (MS) proteomic analyses. Recent...
4.
Stoop M, Visser S, Van Dijk E, Aerts J, Stricker B, Luider T
J Pharm Biomed Anal
. 2017 Oct;
148:89-92.
PMID: 28965049
Most drugs are metabolized in the human body. Therefore, it is essential for therapeutic drug monitoring studies to also take into account the concentrations of drug metabolites. One of the...
5.
Stoop M, Runia T, Stingl C, van der Vuurst de Vries R, Luider T, Hintzen R
Proteomics Clin Appl
. 2017 Sep;
11(11-12).
PMID: 28941200
The pathology of multiple sclerosis is located in the central nervous system, therefore cerebrospinal fluid (CSF) is an attractive biofluid for biomarker research for proteins related to the early stages...
6.
van den Berg C, Duvekot J, Guzel C, Hansson S, de Leeuw T, Steegers E, et al.
Proteomics Clin Appl
. 2016 Sep;
11(1-2).
PMID: 27615121
Purpose: To investigate the cerebrospinal fluid (CSF) proteome of patients with preeclampsia (PE) and normotensive pregnant women, in order to provide a better understanding of brain involvement in PE. Experimental...
7.
Stoop M, Visser S, Van Dijk E, Aerts J, Stricker B, Luider T
J Pharm Biomed Anal
. 2016 May;
128:1-8.
PMID: 27209449
Currently no quantification method exists for potentially therapeutically relevant polyglutamate metabolites of the drug pemetrexed which is used for the treatment of lung carcinoma patients. We developed and tested an...
8.
van Luijn M, van Meurs M, Stoop M, Verbraak E, Wierenga-Wolf A, Melief M, et al.
J Neuropathol Exp Neurol
. 2015 Dec;
75(1):86-98.
PMID: 26683597
Using proteomics, we previously identified chromogranin A (CgA) and clusterin (CLU) as disease-related proteins in the cerebrospinal fluid (CSF) of patients with multiple sclerosis (MS). CgA and CLU are involved...
9.
Singh V, van Pelt E, Stoop M, Stingl C, Ketelslegers I, Neuteboom R, et al.
Neurol Neuroimmunol Neuroinflamm
. 2015 Oct;
2(5):e155.
PMID: 26445729
Objective: To identify CSF biomarkers for multiple sclerosis (MS) in children with an initial acquired CNS demyelinating syndrome (ADS). Methods: CSF was collected from a cohort of 39 children with...
10.
Singh V, Stingl C, Stoop M, Zeneyedpour L, Neuteboom R, Sillevis Smitt P, et al.
J Proteome Res
. 2015 Mar;
14(5):2065-73.
PMID: 25793971
Multiple sclerosis (MScl) frequently is remitted during the third trimester of pregnancy but exacerbated in the first postpartum period. In this context, we investigated protein identification, its abundance, and its...