Marcel P Keller
Overview
Explore the profile of Marcel P Keller including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
439
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0
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Recent Articles
1.
Meyer E, Croxford A, Gnerre C, Kulig P, Murphy M, Jacob E, et al.
J Med Chem
. 2024 May;
67(10):8077-8098.
PMID: 38727100
Migration of immune cells to sites of inflammation is a critical step in the body's response to infections but also during autoimmune flares. Chemokine receptors, members of the GPCR receptors,...
2.
Meyer E, Aanismaa P, Ertel E, Huhn E, Strasser D, Rey M, et al.
J Med Chem
. 2023 Mar;
66(6):4179-4196.
PMID: 36883854
The CXCR3 chemokine receptor is a G protein-coupled receptor mainly expressed on immune cells from the lymphoid lineage, including activated T cells. Binding of its inducible chemokine ligands CXCL9, CXCL10,...
3.
Schlicher L, Kulig P, von Munchow A, Murphy M, Keller M
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35163112
Cenerimod is a potent, selective sphingosine 1-phosphate receptor 1 (S1P) modulator currently investigated in a Phase IIb study in patients with systemic lupus erythematosus (SLE) (NCT03742037). S1P receptor modulators sequester...
4.
Strasser D, Froidevaux S, Sippel V, Gerossier E, Grieder U, Pierlot G, et al.
RMD Open
. 2020 Sep;
6(2).
PMID: 32917831
No abstract available.
5.
Schmidt A, Farine H, Keller M, Sebastian A, Kozera L, Welford R, et al.
J Proteome Res
. 2020 Sep;
19(10):4196-4209.
PMID: 32870689
One of the most important advantages of mass spectrometry is the ability to quantify proteins and their modifications in parallel to obtain a holistic picture of the protein of interest....
6.
Barthlott T, Bosch A, Berkemeier C, Nogales-Cadenas R, Jeker L, Keller M, et al.
Eur J Immunol
. 2015 Mar;
45(6):1760-71.
PMID: 25752506
Regulatory T (Treg) cells are pivotal for the maintenance of peripheral tolerance by controlling self-reactive, chronic, and homeostatic T-cell responses. Here, we report that the increase in Treg-cell suppressive function...
7.
Zuklys S, Gill J, Keller M, Hauri-Hohl M, Zhanybekova S, Balciunaite G, et al.
J Immunol
. 2009 Feb;
182(5):2997-3007.
PMID: 19234195
Thymic T cell development is dependent on a specialized epithelial microenvironment mainly composed of cortical and medullary thymic epithelial cells (TECs). The molecular programs governing the differentiation and maintenance of...
8.
Jeker L, Barthlott T, Keller M, Zuklys S, Hauri-Hohl M, Deng C, et al.
Blood
. 2008 Aug;
112(9):3688-95.
PMID: 18695001
Signals mediated by the transforming growth factor-beta superfamily of growth factors have been implicated in thymic epithelial cell (TEC) differentiation, homeostasis, and function, but a direct reliance on these signals...
9.
Hauri-Hohl M, Zuklys S, Keller M, Jeker L, Barthlott T, Moon A, et al.
Blood
. 2008 May;
112(3):626-34.
PMID: 18474727
The thymus constitutes the primary lymphoid organ responsible for the generation of naive T cells. Its stromal compartment is largely composed of a scaffold of different subsets of epithelial cells...
10.
Alimohammadi M, Bjorklund P, Hallgren A, Pontynen N, Szinnai G, Shikama N, et al.
N Engl J Med
. 2008 Mar;
358(10):1018-28.
PMID: 18322283
Background: Autoimmune polyendocrine syndrome type 1 (APS-1) is a multiorgan autoimmune disorder caused by mutations in AIRE, the autoimmune regulator gene. Though recent studies concerning AIRE deficiency have begun to...