Marcel H Schulz
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Explore the profile of Marcel H Schulz including associated specialties, affiliations and a list of published articles.
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105
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4480
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Recent Articles
1.
Hecker D, Song X, Baumgarten N, Diagel A, Katsaouni N, Li L, et al.
bioRxiv
. 2025 Mar;
PMID: 40027824
Coronary artery disease (CAD) is the leading cause of death worldwide. Recently, hundreds of genomic loci have been shown to increase CAD risk, however, the molecular mechanisms underlying signals from...
2.
Maji R, Leisegang M, Boon R, Schulz M
Trends Genet
. 2025 Jan;
PMID: 39863489
MicroRNAs (miRNAs) are key regulators of gene expression and control cellular functions in physiological and pathophysiological states. miRNAs play important roles in disease, stress, and development, and are now being...
3.
Oo J, Warwick T, Palfi K, Lam F, McNicoll F, Prieto-Garcia C, et al.
Nat Commun
. 2025 Jan;
16(1):131.
PMID: 39747144
The coordination of chromatin remodeling is essential for DNA accessibility and gene expression control. The highly conserved and ubiquitously expressed SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin remodeling complex plays a central role...
4.
Maji R, Schulz M
Methods Mol Biol
. 2024 Dec;
2883:325-341.
PMID: 39702715
MicroRNAs (miRNAs) are a class of small non-coding RNAs (sncRNAs) of length 21-25 nucleotides. These sncRNAs hybridize to repress their target genes and inhibit protein translation, thereby controlling regulatory functions...
5.
Rumpf L, Schulz M
Methods Mol Biol
. 2024 Sep;
2856:341-356.
PMID: 39283463
To reveal gene regulation mechanisms, it is essential to understand the role of regulatory elements, which are possibly distant from gene promoters. Integrative analysis of epigenetic and transcriptomic data can...
6.
Hecker D, Schulz M
Methods Mol Biol
. 2024 Sep;
2856:327-339.
PMID: 39283462
Disentangling the relationship of enhancers and genes is an ongoing challenge in epigenomics. We present STARE, our software to quantify the strength of enhancer-gene interactions based on enhancer activity and...
7.
Brezski A, Murtagh J, Schulz M, Zarnack K
RNA Biol
. 2024 Sep;
21(1):1-16.
PMID: 39257052
CircRNAs are an important class of RNAs with diverse cellular functions in human physiology and disease. A thorough knowledge of circRNAs including their biogenesis and subcellular distribution is important to...
8.
Pacheco M, Gerard D, Mangan R, Chapman A, Hecker D, Kellis M, et al.
bioRxiv
. 2024 Aug;
PMID: 39091778
Background: Constraint-based network modeling is a powerful genomic-scale approach for analyzing cellular metabolism, capturing metabolic variations across tissues and cell types, and defining the metabolic identity essential for identifying disease-associated...
9.
Baumgarten N, Rumpf L, Kessler T, Schulz M
iScience
. 2024 May;
27(5):109765.
PMID: 38736546
Non-coding variants located within regulatory elements may alter gene expression by modifying transcription factor (TF) binding sites, thereby leading to functional consequences. Different TF models are being used to assess...
10.
Jurado M, Tombor L, Arsalan M, Holubec T, Emrich F, Walther T, et al.
Gigascience
. 2024 Apr;
13.
PMID: 38573186
Background: Cardiovascular research heavily relies on mouse (Mus musculus) models to study disease mechanisms and to test novel biomarkers and medications. Yet, applying these results to patients remains a major...