Marc Tittgemeyer
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Explore the profile of Marc Tittgemeyer including associated specialties, affiliations and a list of published articles.
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108
Citations
2736
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Recent Articles
1.
Minere M, Wilhelms H, Kuzmanovic B, Lundh S, Fusca D, Classen A, et al.
Science
. 2025 Feb;
387(6735):750-758.
PMID: 39946455
High sugar-containing foods are readily consumed, even after meals and beyond fullness sensation (e.g., as desserts). Although reward-driven processing of palatable foods can promote overeating, the neurobiological mechanisms that underlie...
2.
Asendorf A, Theis H, Tittgemeyer M, Timmermann L, Fink G, Drzezga A, et al.
Hum Brain Mapp
. 2024 Jul;
45(10):e26776.
PMID: 38958131
Recent studies in Parkinson's disease (PD) patients reported disruptions in dynamic functional connectivity (dFC, i.e., a characterization of spontaneous fluctuations in functional connectivity over time). Here, we assessed whether the...
3.
Banwinkler M, Dzialas V, Rigoux L, Asendorf A, Theis H, Giehl K, et al.
Brain
. 2024 Jun;
147(10):3352-3357.
PMID: 38941444
The relative inability to produce effortful movements is the most specific motor sign of Parkinson's disease, which is primarily characterized by loss of dopaminergic terminals in the putamen. The motor...
4.
Tuscher O, Muthuraman M, Horstmann J, Horta G, Radyushkin K, Baumgart J, et al.
Mol Psychiatry
. 2024 May;
29(11):3537-3552.
PMID: 38806692
Excitation/inhibition (E/I) balance plays important roles in mental disorders. Bioactive phospholipids like lysophosphatidic acid (LPA) are synthesized by the enzyme autotaxin (ATX) at cortical synapses and modulate glutamatergic transmission, and...
5.
Kendrick K, Daumann J, Wagner D, Koester P, Tittgemeyer M, Luo Q, et al.
Psychoradiology
. 2024 Apr;
1(1):3-12.
PMID: 38665308
Background: Amphetamine-type stimulants (ATS) have become a critical public health issue. Animal models have indicated a clear neurotoxic potential of ATSs. In humans, chronic use has been associated with cognitive...
6.
Ruppert-Junck M, Kraling G, Greuel A, Tittgemeyer M, Timmermann L, Drzezga A, et al.
Front Comput Neurosci
. 2024 Feb;
18:1328699.
PMID: 38384375
Parkinson's disease (PD) is currently diagnosed largely on the basis of expert judgement with neuroimaging serving only as a supportive tool. In a recent study, we identified a hypometabolic midbrain...
7.
Theis H, Prange S, Bischof G, Hoenig M, Tittgemeyer M, Timmermann L, et al.
NPJ Parkinsons Dis
. 2023 Nov;
9(1):154.
PMID: 37968562
Impulsive-compulsive behaviour (ICB) is a frequently observed non-motor symptom in early Parkinson's disease after initiating dopamine replacement therapy. At the opposite end of the motivated behaviour spectrum, apathy occurs in...
8.
Hanssen R, Rigoux L, Kuzmanovic B, Iglesias S, Kretschmer A, Schlamann M, et al.
Nat Metab
. 2023 Aug;
5(8):1352-1363.
PMID: 37592007
Survival under selective pressure is driven by the ability of our brain to use sensory information to our advantage to control physiological needs. To that end, neural circuits receive and...
9.
Edwin Thanarajah S, Hanssen R, Melzer C, Tittgemeyer M
Front Endocrinol (Lausanne)
. 2023 May;
14:1130203.
PMID: 37223038
Objective: While variations in the first intron of the (, rs9939609 T/A variant) have long been identified as a major contributor to polygenic obesity, the mechanisms underlying weight gain in...
10.
Edwin Thanarajah S, DiFeliceantonio A, Albus K, Kuzmanovic B, Rigoux L, Iglesias S, et al.
Cell Metab
. 2023 Mar;
35(4):571-584.e6.
PMID: 36958330
Western diets rich in fat and sugar promote excess calorie intake and weight gain; however, the underlying mechanisms are unclear. Despite a well-documented association between obesity and altered brain dopamine...