Marc Lorber
Overview
Explore the profile of Marc Lorber including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
366
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0
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Recent Articles
1.
Schmauch E, Piening B, Mohebnasab M, Xia B, Zhu C, Stern J, et al.
Nat Med
. 2024 May;
30(5):1448-1460.
PMID: 38760586
In a previous study, heart xenografts from 10-gene-edited pigs transplanted into two human decedents did not show evidence of acute-onset cellular- or antibody-mediated rejection. Here, to better understand the detailed...
2.
Eisenson D, Hisadome Y, Santillan M, Iwase H, Chen W, Shimizu A, et al.
Nat Commun
. 2024 Apr;
15(1):3361.
PMID: 38637524
Xenotransplantation represents a possible solution to the organ shortage crisis and is an imminent clinical reality with long-term xenograft survival in pig-to-nonhuman primate (NHP) heart and kidney large animal models,...
3.
Moazami N, Stern J, Khalil K, Kim J, Narula N, Mangiola M, et al.
Nat Med
. 2023 Jul;
29(8):1989-1997.
PMID: 37488288
Genetically modified xenografts are one of the most promising solutions to the discrepancy between the numbers of available human organs for transplantation and potential recipients. To date, a porcine heart...
4.
Griffith B, Goerlich C, Singh A, Rothblatt M, Lau C, Shah A, et al.
N Engl J Med
. 2022 Jun;
387(1):35-44.
PMID: 35731912
A 57-year-old man with nonischemic cardiomyopathy who was dependent on venoarterial extracorporeal membrane oxygenation (ECMO) and was not a candidate for standard therapeutics, including a traditional allograft, received a heart...
5.
Montgomery R, Stern J, Lonze B, Tatapudi V, Mangiola M, Wu M, et al.
N Engl J Med
. 2022 May;
386(20):1889-1898.
PMID: 35584156
Background: Xenografts from genetically modified pigs have become one of the most promising solutions to the dearth of human organs available for transplantation. The challenge in this model has been...
6.
Ariyoshi Y, Takeuchi K, Pomposelli T, Ekanayake-Alper D, Shimizu A, Boyd L, et al.
Xenotransplantation
. 2020 Sep;
28(1):e12642.
PMID: 32909301
Background: Recent advances in gene editing technology have enabled the production of multi-knockout (KO) and transgenic pigs in order to overcome immunologic barriers in xenotransplantation (XTx). However, the genetic manipulations...
7.
Hakim W, Sheikh S, Inayat I, Caldwell C, Smith D, Lorber M, et al.
J Clin Gastroenterol
. 2009 Jan;
43(5):477-81.
PMID: 19142165
Goals: To determine the efficacy and safety of combination therapy in patients with hepatitis C virus (HCV) and end-stage renal disease (ESRD). Background: There is little data on the treatment...
8.
Karamehic J, Lorber M, Formica R, Gavrankapetanovic F, Heljic B, Subasic D, et al.
Bosn J Basic Med Sci
. 2006 Sep;
6(3):43-7.
PMID: 16995847
In practical terms, regardless of HLA compatibility level, whenever tissues are transplanted from one person to another it is essential to suppress the immune response of the recipient. A variety...
9.
Delmonico F, Morrissey P, Lipkowitz G, Stoff J, Himmelfarb J, Harmon W, et al.
Am J Transplant
. 2004 Sep;
4(10):1628-34.
PMID: 15367217
Kidney transplantation from live donors achieves an excellent outcome regardless of human leukocyte antigen (HLA) mismatch. This development has expanded the opportunity of kidney transplantation from unrelated live donors. Nevertheless,...