Marc Lapointe
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Explore the profile of Marc Lapointe including associated specialties, affiliations and a list of published articles.
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35
Citations
340
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Recent Articles
11.
Gupta A, Rezvani R, Lapointe M, Poursharifi P, Marceau P, Tiwari S, et al.
PLoS One
. 2014 Apr;
9(4):e95478.
PMID: 24743347
Background: The central component of the complement system, C3, is associated with obesity, metabolic syndrome and cardiovascular disease however the underlying reasons are unknown. In the present study we evaluated...
12.
Poursharifi P, Rezvani R, Gupta A, Lapointe M, Marceau P, Tchernof A, et al.
Mediators Inflamm
. 2014 Feb;
2014:413921.
PMID: 24523571
Adipose tissue receptors C5aR and C5L2 and their heterodimerization/functionality and interaction with ligands C5a and acylation stimulating protein (ASP) have been evaluated in cell and rodent studies. Their contribution to...
13.
Gupta A, Miegueu P, Lapointe M, Poirier P, Martin J, Bastien M, et al.
PLoS One
. 2014 Jan;
9(1):e84803.
PMID: 24400115
Context: Orexin is a recently identified neuropeptide hormone. Objectives: Acute and long-term post-bariatric changes in Orexin and relationship to post-operative metabolic outcomes. Design And Participants: Men and women undergoing biliopancreatic...
14.
Poursharifi P, Lapointe M, Fisette A, Lu H, Roy C, Munkonda M, et al.
Mol Cell Endocrinol
. 2014 Jan;
382(1):325-333.
PMID: 24397921
Recent studies suggested that the immunometabolic receptors; C5aR and C5L2, constitutively self-associate into homo-/heterodimers and that acylation stimulating protein (ASP/C3adesArg) or C5a treatment of adipocytes increased their colocalization. The present...
15.
Graffagnino C, Bergese S, Love J, Schneider D, Lazaridis C, Lapointe M, et al.
Cerebrovasc Dis
. 2013 Oct;
36(3):173-80.
PMID: 24135526
Background: Intracerebral hemorrhage (ICH) causes 10-15% of primary strokes, with mortality related to hematoma volume. Blood pressure (BP) reduction may attenuate hematoma expansion. ACCELERATE (the Evaluation of Patients with Acute...
16.
Ziai W, Tuhrim S, Lane K, McBee N, Lees K, Dawson J, et al.
Int J Stroke
. 2013 Sep;
9(4):536-42.
PMID: 24033910
Background: In adults, intraventricular thrombolytic therapy with recombinant tissue plasminogen activator (rtPA) facilitates resolution of intraventricular haemorrhage (IVH), reduces intracranial pressure, decreases duration of cerebrospinal fluid diversion, and may ameliorate...
17.
Fisette A, Lapointe M, Cianflone K
Biochem Biophys Res Commun
. 2013 Jul;
437(3):403-7.
PMID: 23831465
Acylation stimulating protein (ASP) is an adipokine derived from the immune complement system that is involved in energy homeostasis and inflammation. ASP acts on and correlates positively with postprandial fat...
18.
Fisette A, Poursharifi P, Oikonomopoulou K, Munkonda M, Lapointe M, Cianflone K
Mediators Inflamm
. 2013 Jun;
2013:713284.
PMID: 23737652
Acylation stimulating protein (ASP) is an adipokine derived from the immune complement system, which stimulates fat storage and is typically increased in obesity, type 2 diabetes, and cardiovascular disease. Using...
19.
Roy C, Gupta A, Fisette A, Lapointe M, Poursharifi P, Richard D, et al.
PLoS One
. 2013 May;
8(5):e62531.
PMID: 23667486
Objective: To investigate the impact of whole body C5a receptor (C5aR) deficiency on energy metabolism and fat storage. Design: Male wildtype (WT) and C5aR knockout (C5aRKO) mice were fed a...
20.
Poursharifi P, Lapointe M, Petrin D, Devost D, Gauvreau D, Hebert T, et al.
Cell Signal
. 2012 Dec;
25(4):910-8.
PMID: 23268185
Obesity is associated with inflammation characterized by increased infiltration of macrophages into adipose tissue. C5aR-like receptor 2 (C5L2) has been identified as a receptor for acylation-stimulating protein (ASP) and the...