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Marc B Brown

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Articles 70
Citations 895
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Recent Articles
1.
van der Weerden N, Parisi K, McKenna J, Hayes B, Harvey P, Quimbar P, et al.
J Fungi (Basel) . 2023 Nov; 9(11). PMID: 37998916
Onychomycosis, or fungal nail infection, causes not only pain and discomfort but can also have psychological and social consequences for the patient. Treatment of onychomycosis is complicated by the location...
2.
Beebeejaun M, Brown M, Hutter V, Kravitz L, McAuley W
Skin Health Dis . 2023 Jun; 3(3):e215. PMID: 37275414
Background: Topical corticosteroids (TCS) and emollients are developed independently by the pharmaceutical industry but are often used together in practice. There is potential for the TCS and emollient formulations to...
3.
Neil J, Brown M, Lenn J, Williams A
Int J Pharm . 2022 Mar; 618:121648. PMID: 35276230
Although animal models have been extensively used to evaluate human topical therapeutics, they exhibit marked physiological differences to human skin. Our objective was to develop a human ex vivo skin...
4.
Jessica E Neil M, Lenn J, Brown M, Williams A
Int J Pharm . 2022 Feb; 617:121610. PMID: 35202723
Several in vitro models have been designed as test systems for inflammatory skin conditions, commonly using cell-culture or reconstructed human epidermis approaches. However, these systems poorly recapitulate the physiology and,...
5.
Neil J, Brown M, Williams A
Sci Rep . 2020 Dec; 10(1):21192. PMID: 33273665
The development of in vitro and ex vivo models to mimic human illness is important not only for scientific understanding and investigating therapeutic approaches but also to mitigate animal testing...
6.
Draelos Z, Ports W, Vlahos B, Yeoh T, Wu-Linhares D, Brown M, et al.
J Am Acad Dermatol . 2020 Oct; 83(6):1801-1803. PMID: 33069458
No abstract available.
7.
Turner R, Wevrett S, Edmunds S, Brown M, Atkinson R, Adegoke O, et al.
Clin Pharmacol . 2020 Apr; 12:13-20. PMID: 32273779
Objective: Flurbiprofen 8.75 mg spray and lozenge have a rapid onset of action for sore throat relief, suggesting local action, although tissue penetration and the mechanism of local relief have...
8.
Shafaie S, Hutter V, Brown M, Cook M, Chau D
Int J Pharm . 2018 Aug; 550(1-2):207-215. PMID: 30138706
The human vitreous humour is a complex gel structure whose composition and physical properties can vary considerably from person to person and also change with age. To date, the viscoelastic...
9.
Shetage S, Traynor M, Brown M, Chilcott R
Lipids Health Dis . 2018 Aug; 17(1):194. PMID: 30131075
Background: "Residual skin surface components" (RSSC) is the collective term used for the superficial layer of sebum, residue of sweat, small quantities of intercellular lipids and components of natural moisturising...
10.
Cook M, Brown M
J Control Release . 2017 Dec; 270:145-157. PMID: 29223536
Intravaginal drug delivery can elicit a local effect, or deliver drugs systemically without hepatic first pass metabolism. There are a number of emerging areas in intravaginal drug delivery, but the...