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Marc A van Driel

Explore the profile of Marc A van Driel including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 1203
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Recent Articles
1.
Ederveen A, Lai Y, van Driel M, Gerats T, Peters J
BMC Genomics . 2015 Apr; 16:89. PMID: 25879408
Background: Crossing over assures the correct segregation of the homologous chromosomes to both poles of the dividing meiocyte. This exchange of DNA creates new allelic combinations thus increasing the genetic...
2.
Mihaleva V, Te Beek T, van Zimmeren F, Moco S, Laatikainen R, Niemitz M, et al.
Anal Chem . 2013 Aug; 85(18):8700-7. PMID: 23930710
Identification of natural compounds, especially secondary metabolites, has been hampered by the lack of easy to use and accessible reference databases. Nuclear magnetic resonance (NMR) spectroscopy is the most selective...
3.
Jimenez R, Albar J, Bhak J, Blatter M, Blicher T, Brazas M, et al.
Bioinformatics . 2013 Jun; 29(15):1919-21. PMID: 23742982
Summary: We present iAnn, an open source community-driven platform for dissemination of life science events, such as courses, conferences and workshops. iAnn allows automatic visualisation and integration of customised event...
4.
Vos M, Te Beek T, van Driel M, Huynen M, Eyre-Walker A, van Passel M
PLoS One . 2013 May; 8(5):e62447. PMID: 23671597
Quantifying patterns of adaptive divergence between taxa is a major goal in the comparative and evolutionary study of prokaryote genomes. When applied appropriately, the McDonald-Kreitman (MK) test is a powerful...
5.
Rojas-Cherto M, Van Vliet M, Peironcely J, van Doorn R, Kooyman M, te Beek T, et al.
Bioinformatics . 2012 Aug; 28(20):2707-9. PMID: 22851531
Unlabelled: Identification of metabolites using high-resolution multi-stage mass spectrometry (MS(n)) data is a significant challenge demanding access to all sorts of computational infrastructures. MetiTree is a user-friendly, web application dedicated...
6.
Salcedo-Amaya A, van Driel M, Alako B, Trelle M, van den Elzen A, Cohen A, et al.
Proc Natl Acad Sci U S A . 2009 Jun; 106(24):9655-60. PMID: 19497874
Epigenome profiling has led to the paradigm that promoters of active genes are decorated with H3K4me3 and H3K9ac marks. To explore the epigenome of Plasmodium falciparum asexual stages, we performed...
7.
Welboren W, van Driel M, Janssen-Megens E, van Heeringen S, Sweep F, Span P, et al.
EMBO J . 2009 Apr; 28(10):1418-28. PMID: 19339991
We used ChIP-Seq to map ERalpha-binding sites and to profile changes in RNA polymerase II (RNAPII) occupancy in MCF-7 cells in response to estradiol (E2), tamoxifen or fulvestrant. We identify...
8.
Smeenk L, van Heeringen S, Koeppel M, van Driel M, Bartels S, Akkers R, et al.
Nucleic Acids Res . 2008 May; 36(11):3639-54. PMID: 18474530
The tumor suppressor p53 is a sequence-specific transcription factor, which regulates the expression of target genes involved in different stress responses. To understand p53's essential transcriptional functions, unbiased analysis of...
9.
Hatzis P, van der Flier L, van Driel M, Guryev V, Nielsen F, Denissov S, et al.
Mol Cell Biol . 2008 Feb; 28(8):2732-44. PMID: 18268006
Wnt signaling activates gene expression through the induced formation of complexes between DNA-binding T-cell factors (TCFs) and the transcriptional coactivator beta-catenin. In colorectal cancer, activating Wnt pathway mutations transform epithelial...
10.
van Driel M, Brunner H
Hum Genomics . 2006 Jul; 2(6):429-32. PMID: 16848981
With the explosion in genomic and functional genomics information, methods for disease gene identification are rapidly evolving. Databases are now essential to the process of selecting candidate disease genes. Combining...