Mara J Kroner
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Explore the profile of Mara J Kroner including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
173
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Recent Articles
1.
Schaftenaar F, van Dam A, de Bruin G, Depuydt M, de Mol J, Amersfoort J, et al.
Arterioscler Thromb Vasc Biol
. 2024 Apr;
44(6):1346-1364.
PMID: 38660806
Background: Atherosclerosis is the major underlying pathology of cardiovascular disease and is driven by dyslipidemia and inflammation. Inhibition of the immunoproteasome, a proteasome variant that is predominantly expressed by immune...
2.
Douna H, De Mol J, Amersfoort J, Schaftenaar F, Kiss M, Suur B, et al.
Front Cardiovasc Med
. 2022 Feb;
9:781436.
PMID: 35187121
B and T cells are interconnected in the T follicular helper-germinal center B cell (T-GC B cell) axis, which is hyperactive during atherosclerosis development and loss of control along this...
3.
Bot I, Velden D, Bouwman M, Kroner M, Kuiper J, Quax P, et al.
Cells
. 2020 Mar;
9(3).
PMID: 32178480
Mast cells have been associated with arteriogenesis and collateral formation. In advanced human atherosclerotic plaques, mast cells have been shown to colocalize with plaque neovessels, and mast cells have also...
4.
Schaftenaar F, Amersfoort J, Douna H, Kroner M, Foks A, Bot I, et al.
Sci Rep
. 2019 Nov;
9(1):17391.
PMID: 31757993
Cardiovascular diseases form the most common cause of death worldwide, with atherosclerosis as main etiology. Atherosclerosis is marked by cholesterol rich lipoprotein deposition in the artery wall, evoking a pathogenic...
5.
van Ingen E, Foks A, Kroner M, Kuiper J, Quax P, Bot I, et al.
Mol Ther Nucleic Acids
. 2019 Nov;
18:638-649.
PMID: 31689618
We have previously shown that third-generation antisense (3GA) inhibition of 14q32 microRNA (miRNA)-494 reduced early development of atherosclerosis. However, patients at risk of atherosclerotic complications generally present with advanced and...
6.
Douna H, Amersfoort J, Schaftenaar F, Kroner M, Kiss M, Slutter B, et al.
Cardiovasc Res
. 2019 Jun;
116(2):295-305.
PMID: 31150053
Aims: The immune system is strongly involved in atherosclerosis and immune regulation generally leads to attenuated atherosclerosis. B- and T-lymphocyte attenuator (BTLA) is a novel co-receptor that negatively regulates the...
7.
Hoekstra M, Nahon J, de Jong L, Kroner M, de Leeuw L, Van Eck M
Biochim Biophys Acta Mol Basis Dis
. 2019 Feb;
1865(6):1402-1409.
PMID: 30776415
The nuclear receptor liver X receptor (LXR) impacts on cholesterol metabolism as well as hepatic lipogenesis via transcriptional regulation. It is proposed that inhibition of the protein arginine methyltransferase 3...
8.
Hoekstra M, Ouweneel A, Nahon J, van der Geest R, Kroner M, van der Sluis R, et al.
Biochim Biophys Acta Mol Cell Biol Lipids
. 2019 Jan;
1864(4):443-451.
PMID: 30633988
Objective: Since cholesterol is the sole precursor for glucocorticoid synthesis, it is hypothesized that genetic defects in proteins that impact the cellular cholesterol pool may underlie glucocorticoid insufficiency in humans....
9.
Amersfoort J, Douna H, Schaftenaar F, Foks A, Kroner M, van Santbrink P, et al.
Front Immunol
. 2019 Jan;
9:2937.
PMID: 30619297
Macroautophagy (or autophagy) is a conserved cellular process in which cytoplasmic cargo is targeted for lysosomal degradation. Autophagy is crucial for the functional integrity of different subsets of T cells...
10.
Kritikou E, van Duijn J, Nahon J, van der Heijden T, Bouwman M, Groeneveldt C, et al.
Atherosclerosis
. 2018 Dec;
280:132-139.
PMID: 30513408
Background And Aims: The development of atherosclerosis is tightly regulated by the innate and adaptive immune system. Communication between these two compartments occurs, among others, upon presentation of lipid antigens...