Manya Sabherwal
Overview
Explore the profile of Manya Sabherwal including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
142
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Recent Articles
1.
Monk B, Keniya M, Sabherwal M, Wilson R, Graham D, Hassan H, et al.
Antimicrob Agents Chemother
. 2018 Nov;
63(1).
PMID: 30397057
Tetrazole antifungals designed to target fungal lanosterol 14α-demethylase (LDM) appear to be effective against a range of fungal pathogens. In addition, a crystal structure of the catalytic domain of LDM...
2.
Keniya M, Sabherwal M, Wilson R, Woods M, Sagatova A, Tyndall J, et al.
Antimicrob Agents Chemother
. 2018 Aug;
62(11).
PMID: 30126961
Targeting lanosterol 14α-demethylase (LDM) with azole drugs provides prophylaxis and treatments for superficial and disseminated fungal infections, but cure rates are not optimal for immunocompromised patients and individuals with comorbidities....
3.
Tyndall J, Sabherwal M, Sagatova A, Keniya M, Negroni J, Wilson R, et al.
PLoS One
. 2016 Dec;
11(12):e0167485.
PMID: 27907120
Azole antifungals, known as demethylase inhibitors (DMIs), target sterol 14α-demethylase (CYP51) in the ergosterol biosynthetic pathway of fungal pathogens of both plants and humans. DMIs remain the treatment of choice...
4.
Sagatova A, Keniya M, Wilson R, Sabherwal M, Tyndall J, Monk B
Sci Rep
. 2016 May;
6:26213.
PMID: 27188873
Emergence of fungal strains showing resistance to triazole drugs can make treatment of fungal disease problematic. Triazole resistance can arise due to single mutations in the drug target lanosterol 14α-demethylase...
5.
Ha M, Sabherwal M, Duncan E, Stevens S, Stockwell P, McConnell M, et al.
PLoS One
. 2015 Oct;
10(10):e0139774.
PMID: 26447763
An in-depth proteomic study of sheep milk whey is reported and compared to the data available in the literature for the cow whey proteome. A combinatorial peptide ligand library kit...
6.
Pilbrow J, Sabherwal M, Garama D, Carne A
PLoS One
. 2014 Sep;
9(9):e106465.
PMID: 25192378
A previously uncharacterized protein with a carotenoid-binding function has been isolated and characterized from the gonad of the New Zealand sea urchin Evechinus chloroticus. The main carotenoid bound to the...