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Manway Liu

Explore the profile of Manway Liu including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 7679
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Recent Articles
1.
Vitko D, Chou W, Nouri Golmaei S, Lee J, Belthangady C, Blume J, et al.
J Proteome Res . 2024 Jan; 23(3):929-938. PMID: 38225219
Mass spectrometry (MS) is a valuable tool for plasma proteome profiling and disease biomarker discovery. However, wide-ranging plasma protein concentrations, along with technical and biological variabilities, present significant challenges for...
2.
Chitnis T, Glanz B, Gonzalez C, Healy B, Saraceno T, Sattarnezhad N, et al.
NPJ Digit Med . 2019 Dec; 2:123. PMID: 31840094
Technological advances in passive digital phenotyping present the opportunity to quantify neurological diseases using new approaches that may complement clinical assessments. Here, we studied multiple sclerosis (MS) as a model...
3.
Badgeley M, Zech J, Oakden-Rayner L, Glicksberg B, Liu M, Gale W, et al.
NPJ Digit Med . 2019 Jul; 2:31. PMID: 31304378
Hip fractures are a leading cause of death and disability among older adults. Hip fractures are also the most commonly missed diagnosis on pelvic radiographs, and delayed diagnosis leads to...
4.
Ghandi M, Huang F, Jane-Valbuena J, Kryukov G, Lo C, McDonald 3rd E, et al.
Nature . 2019 May; 569(7757):503-508. PMID: 31068700
Large panels of comprehensively characterized human cancer models, including the Cancer Cell Line Encyclopedia (CCLE), have provided a rigorous framework with which to study genetic variants, candidate targets, and small-molecule...
5.
Barretina J, Caponigro G, Stransky N, Venkatesan K, Margolin A, Kim S, et al.
Nature . 2018 Dec; 565(7738):E5-E6. PMID: 30559381
No abstract available.
6.
Zech J, Badgeley M, Liu M, Costa A, Titano J, Oermann E
PLoS Med . 2018 Nov; 15(11):e1002683. PMID: 30399157
Background: There is interest in using convolutional neural networks (CNNs) to analyze medical imaging to provide computer-aided diagnosis (CAD). Recent work has suggested that image classification CNNs may not generalize...
7.
Badgeley M, Liu M, Glicksberg B, Shervey M, Zech J, Shameer K, et al.
Bioinformatics . 2018 Oct; 35(9):1610-1612. PMID: 30304439
Motivation: Radiologists have used algorithms for Computer-Aided Diagnosis (CAD) for decades. These algorithms use machine learning with engineered features, and there have been mixed findings on whether they improve radiologists'...
8.
Lerin C, Goldfine A, Boes T, Liu M, Kasif S, Dreyfuss J, et al.
Mol Metab . 2016 Oct; 5(10):926-936. PMID: 27689005
Objective: Plasma levels of branched-chain amino acids (BCAA) are consistently elevated in obesity and type 2 diabetes (T2D) and can also prospectively predict T2D. However, the role of BCAA in...
9.
Elkabets M, Pazarentzos E, Juric D, Sheng Q, Pelossof R, Brook S, et al.
Cancer Cell . 2015 Apr; 27(4):533-46. PMID: 25873175
Phosphoinositide-3-kinase (PI3K)-α inhibitors have shown clinical activity in squamous cell carcinomas (SCCs) of head and neck (H&N) bearing PIK3CA mutations or amplification. Studying models of therapeutic resistance, we have observed...
10.
Huynh H, Hao H, Chan S, Chen D, Ong R, Soo K, et al.
Mol Cancer Ther . 2015 Mar; 14(5):1224-35. PMID: 25724664
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and hyperactivation of mTOR signaling plays a pivotal role in HCC tumorigenesis. Tuberous sclerosis complex (TSC), a heterodimer...