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Manon Desgres

Explore the profile of Manon Desgres including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 117
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Recent Articles
1.
Van den Bossche V, Vignau J, Vigneron E, Rizzi I, Zaryouh H, Wouters A, et al.
Nat Commun . 2025 Jan; 16(1):1237. PMID: 39890801
Anti-epidermal growth factor receptor (EGFR) therapy (cetuximab) shows a limited clinical benefit for patients with locally advanced or recurrent/metastatic head and neck squamous cell carcinoma (HNSCC), due to the frequent...
2.
Derouane F, Desgres M, Moroni C, Ambroise J, Berliere M, Van Bockstal M, et al.
Breast Cancer Res . 2024 Feb; 26(1):29. PMID: 38374113
Background: Neoadjuvant chemotherapy (NAC) is the standard of care for patients with early-stage triple negative breast cancers (TNBC). However, more than half of TNBC patients do not achieve a pathological...
3.
Desgres M, Lima Correa B, Petrusca L, Autret G, Pezzana C, Marigny C, et al.
Front Cardiovasc Med . 2023 Jul; 10:1206279. PMID: 37485274
Background: Current treatments of chemotherapy-induced cardiomyopathy (CCM) are of limited efficacy. We assessed whether repeated intravenous injections of human extracellular vesicles from cardiac progenitor cells (EV-CPC) could represent a new...
4.
Pezzana C, Cras A, Simeliere F, Guesdon R, Desgres M, Lima Correa B, et al.
Biomaterials . 2022 Nov; 291:121877. PMID: 36347132
Extracellular vesicles (EV) are increasingly recognized as a therapeutic option in heart failure. They are usually administered by direct intramyocardial injections with the caveat of a rapid wash-out from the...
5.
Lima Correa B, El Harane N, Desgres M, Perotto M, Alayrac P, Guillas C, et al.
Theranostics . 2021 Nov; 11(20):10114-10124. PMID: 34815807
Extracellular vesicles (EV) mediate the therapeutic effects of stem cells but it is unclear whether this involves cardiac regeneration mediated by endogenous cardiomyocyte proliferation. Bi-transgenic MerCreMer/ZEG (n = 15/group) and...
6.
Grifone R, Saquet A, Desgres M, Sangiorgi C, Gargano C, Li Z, et al.
Sci Rep . 2021 May; 11(1):9423. PMID: 33941806
Skeletal muscle has a remarkable capacity of regeneration after injury, but the regulatory network underlying this repair process remains elusive. RNA-binding proteins play key roles in the post-transcriptional regulation of...
7.
Lima Correa B, El Harane N, Gomez I, Hocine H, Vilar J, Desgres M, et al.
Cardiovasc Res . 2020 Feb; 117(1):292-307. PMID: 32049348
Aims: The cardioprotective effects of human induced pluripotent stem cell-derived cardiovascular progenitor cells (CPC) are largely mediated by the paracrine release of extracellular vesicles (EV). We aimed to assess the...
8.
Desgres M, Menasche P
Cell Stem Cell . 2019 Nov; 25(5):594-606. PMID: 31703770
Although the clinical outcomes of cell therapy trials have not met initial expectations, emerging evidence suggests that injury-mediated tissue damage might benefit from the delivery of cells or their secreted...
9.
Desgres M, Menasche P
Med Sci (Paris) . 2019 Oct; 35(10):771-778. PMID: 31625899
Although the first wave of cell therapy trials has not commonly yielded clinically meaningful improvements, some encouraging hints have emerged which suggest that stem cells or their secreted products could...