Manolo Carta
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Explore the profile of Manolo Carta including associated specialties, affiliations and a list of published articles.
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65
Citations
1961
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Recent Articles
1.
Bourque M, Morissette M, Isenbrandt A, Giatti S, Melcangi R, Carta M, et al.
Front Neuroendocrinol
. 2024 Oct;
75:101156.
PMID: 39353534
Parkinson's disease (PD) is characterized by motor symptoms due to loss of brain dopamine and non-motor symptoms, including gastrointestinal disorders. Although there is no cure for PD, symptomatic treatments are...
2.
Scheggi S, Concas L, Corsi S, Carta M, Melis M, Frau R
Neurosci Biobehav Rev
. 2024 Aug;
164:105842.
PMID: 39103066
Imbalances in dopamine activity significantly contribute to the pathophysiology of several neuropsychiatric disorders, including addiction, ADHD, schizophrenia, impulse control disorders, and Parkinson's Disease. Neuro(active)steroids, comprising endogenous steroids that finely modulate...
3.
Marano M, Pilotto A, Padovani A, Gupta D, Vivacqua G, Magliozzi A, et al.
J Neurol
. 2024 May;
271(7):3711-3720.
PMID: 38720139
Background: Parkinson's disease (PD) patients are frequently exposed to antidepressant medications (ADMs). Norepinephrine (NE) and serotonin (5HT) systems have a role in levodopa-induced dyskinesias (LID) pathophysiology. Methods: We performed a...
4.
Corsi S, Scheggi S, Pardu A, Braccagni G, Caruso D, Cioffi L, et al.
Exp Neurol
. 2023 Dec;
373:114640.
PMID: 38104017
No abstract available.
5.
Valsecchi V, Errico F, Bassareo V, Marino C, Nuzzo T, Brancaccio P, et al.
Commun Biol
. 2023 Nov;
6(1):1155.
PMID: 37957344
Beyond motor neuron degeneration, homozygous mutations in the survival motor neuron 1 (SMN1) gene cause multiorgan and metabolic defects in patients with spinal muscular atrophy (SMA). However, the precise biochemical...
6.
Serra M, Di Maio A, Bassareo V, Nuzzo T, Errico F, Servillo F, et al.
Neurobiol Dis
. 2023 Jul;
184:106226.
PMID: 37451474
Loss of dopaminergic midbrain neurons perturbs l-serine and d-serine homeostasis in the post-mortem caudate putamen (CPu) of Parkinson's disease (PD) patients. However, it is unclear whether the severity of dopaminergic...
7.
Di Maio A, Nuzzo T, Gilio L, Serra M, Buttari F, Errico F, et al.
Neurobiol Dis
. 2023 Jun;
184:106203.
PMID: 37336364
L-serine generated in astrocytes plays a pivotal role in modulating essential neurometabolic processes, while its enantiomer, D-serine, specifically regulates NMDA receptor (NMDAR) signalling. Despite their physiological relevance in modulating cerebral...
8.
Corsi S, Scheggi S, Pardu A, Braccagni G, Caruso D, Cioffi L, et al.
Exp Neurol
. 2023 Mar;
363:114370.
PMID: 36878398
Growing preclinical and clinical evidence highlights neurosteroid pathway imbalances in Parkinson's Disease (PD) and L-DOPA-induced dyskinesias (LIDs). We recently reported that 5α-reductase (5AR) inhibitors dampen dyskinesias in parkinsonian rats; however,...
9.
Errico F, Marino C, Grimaldi M, Nuzzo T, Bassareo V, Valsecchi V, et al.
Biomolecules
. 2022 Oct;
12(10).
PMID: 36291640
Intrathecal delivery of Nusinersen-an antisense oligonucleotide that promotes survival motor neuron (SMN) protein induction-is an approved therapy for spinal muscular atrophy (SMA). Here, we employed nuclear magnetic resonance (NMR) spectroscopy...
10.
Meloni M, Figorilli M, Carta M, Tamburrino L, Cannas A, Sanna F, et al.
Sleep Breath
. 2021 Aug;
26(3):1023-1031.
PMID: 34403081
Purpose: Altered serotonergic neurotransmission may contribute to the non-motor features commonly associated with Parkinson's disease (PD) such as sleep disorders. The 5-hydroxytryptophan (5-HTP) is the intermediate metabolite of L-tryptophan in...