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Manoj M Wagle

Explore the profile of Manoj M Wagle including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Wagle M, Long S, Chen C, Liu C, Yang P
Bioinformatics . 2024 Jun; 40(6). PMID: 38889275
Motivation: Single-cell omics technologies have enabled the quantification of molecular profiles in individual cells at an unparalleled resolution. Deep learning, a rapidly evolving sub-field of machine learning, has instilled a...
2.
Huang H, Liu C, Wagle M, Yang P
Genome Biol . 2023 Nov; 24(1):259. PMID: 37950331
Background: Feature selection is an essential task in single-cell RNA-seq (scRNA-seq) data analysis and can be critical for gene dimension reduction and downstream analyses, such as gene marker identification and...
3.
Kolathur K, Mallya S, Barve S, Bojja S, Wagle M
Int J Biochem Cell Biol . 2023 Jul; 162:106445. PMID: 37453225
The faithful splicing of pre-mRNA is critical for accurate gene expression. Dysregulation of pre-mRNA splicing has been associated with several human diseases including cancer. The ubiquitin-like protein Hub1/UBL5 binds to...
4.
Sierk M, Ratnayake S, Wagle M, Chen B, Park B, Wang J, et al.
BMC Bioinformatics . 2023 Jun; 24(1):244. PMID: 37296383
Background: High throughput experiments in cancer and other areas of genomic research identify large numbers of sequence variants that need to be evaluated for phenotypic impact. While many tools exist...
5.
Wagle M, Kedige A, Kabekkodu S, Mallya S
Asian Pac J Cancer Prev . 2023 May; 24(5):1601-1610. PMID: 37247279
Background: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy associated with rapid progression and an abysmal prognosis. Previous research has shown that chronic pancreatitis can significantly increase the risk...