Manoj Kandpal
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Explore the profile of Manoj Kandpal including associated specialties, affiliations and a list of published articles.
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20
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538
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Recent Articles
1.
Sarami I, Hekman K, Gupta A, Snider J, Ivancic D, Zec M, et al.
bioRxiv
. 2025 Mar;
PMID: 40060393
Metabolic pathways play a critical role in driving differentiation but remain poorly understood in the development of kidney organoids. In this study, parallel metabolite and transcriptome profiling of differentiating human...
2.
Idnay B, Xu Z, Adams W, Adibuzzaman M, Anderson N, Bahroos N, et al.
Npj Health Syst
. 2025 Jan;
2(1):4.
PMID: 39872195
This study reports a comprehensive environmental scan of the generative AI (GenAI) infrastructure in the national network for clinical and translational science across 36 institutions supported by the CTSA Program...
3.
Sadeghi M, Salama M, Chiappone S, Huang A, Resnick A, Kandpal M, et al.
Cell Rep
. 2024 Dec;
43(12):115026.
PMID: 39630579
Activating mutations in the epidermal growth factor receptor (EGFR) promote ligand-independent signaling; however, the mechanisms involved are poorly defined, and it is unknown whether this generates specific vulnerabilities. We previously...
4.
Tai Y, Chow A, Han S, Coker C, Ma W, Gu Y, et al.
EMBO Mol Med
. 2024 Jul;
16(8):1957-1980.
PMID: 38956205
Acquired resistance to PARP inhibitors (PARPi) remains a treatment challenge for BRCA1/2-mutant breast cancer that drastically shortens patient survival. Although several resistance mechanisms have been identified, none have been successfully...
5.
Kost R, Devine R, Fernands M, Gottesman R, Kandpal M, MacArthur R, et al.
J Clin Transl Sci
. 2023 May;
7(1):e104.
PMID: 37250985
Introduction: Clinical trials are a vital component of translational science, providing crucial information on the efficacy and safety of new interventions and forming the basis for regulatory approval and/or clinical...
6.
Levitsky J, Kandpal M, Guo K, Kleiboeker S, Sinha R, Abecassis M
Am J Transplant
. 2021 Sep;
22(2):532-540.
PMID: 34510731
Donor-derived cell-free DNA (dd-cfDNA) has been evaluated as a rejection marker in organ transplantation. This study sought to assess the utility of dd-cfDNA to diagnose graft injury in liver transplant...
7.
Levitsky J, Kandpal M, Guo K, Zhao L, Kurian S, Whisenant T, et al.
Transplantation
. 2021 Aug;
106(5):1004-1011.
PMID: 34342962
Background: Noninvasive biomarkers distinguishing early immune activation before acute rejection (AR) could more objectively inform immunosuppression management in liver transplant recipients (LTRs). We previously reported a genomic profile distinguishing LTR...
8.
Forte E, Butun F, Marinaccio C, Schipma M, Piunti A, Schroeder M, et al.
J Virol
. 2021 Mar;
95(11).
PMID: 33731453
HCMV establishes latency in myeloid cells. Using the Kasumi-3 latency model, we previously showed that lytic gene expression is activated prior to establishment of latency in these cells. The early...
9.
Kumthekar P, Ko C, Paunesku T, Dixit K, Sonabend A, Bloch O, et al.
Sci Transl Med
. 2021 Mar;
13(584).
PMID: 33692132
Glioblastoma (GBM) is one of the most difficult cancers to effectively treat, in part because of the lack of precision therapies and limited therapeutic access to intracranial tumor sites due...
10.
Kandpal M, Davuluri R
Stat Appl
. 2020 Sep;
18(1):253-268.
PMID: 32984664
RNA viral genomes have very high mutations rates. As infection spreads in the host populations, different viral lineages emerge acquiring independent mutations that can lead to varied infection and death...