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Mannie M Y Fan

Explore the profile of Mannie M Y Fan including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 314
Followers 0
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Recent Articles
1.
Carol H, Fan M, Harasym T, Boehm I, Mayer L, Houghton P, et al.
Pediatr Blood Cancer . 2014 Sep; 62(1):65-71. PMID: 25203866
Background: CPX-351, a liposomal formulation of cytarabine and daunorubicin co-encapsulated at an optimized synergistic 5:1 molar ratio, has demonstrated improved clinical outcomes over conventional cytarabine/daunorubicin treatment in a randomized phase...
2.
Cowan C, Fan M, Fan J, Shehadeh J, Zhang L, Graham R, et al.
J Neurosci . 2008 Nov; 28(48):12725-35. PMID: 19036965
Huntington disease (HD), caused by CAG expansion in the ubiquitously expressed huntingtin gene, is characterized by early dysfunction and death of striatal medium-sized spiny neurons (MSNs). Previous work has shown...
3.
Fan M, Zhang H, Hayden M, Pelech S, Raymond L
J Neurochem . 2007 Nov; 104(3):790-805. PMID: 17971125
Huntington's disease is caused by a polyglutamine expansion in the huntingtin (htt) protein, and previous data indicate that over-activation of NMDA receptors (NMDARs) may be involved in the selective degeneration...
4.
Fan M, Fernandes H, Zhang L, Hayden M, Raymond L
J Neurosci . 2007 Apr; 27(14):3768-79. PMID: 17409241
Overactivation of NMDA receptors (NMDARs) is believed to play a role in degeneration of striatal medium-sized spiny neurons (MSNs) in Huntington's disease (HD). This hereditary disorder is caused by an...
5.
Fan M, Fan J
J Neurosci . 2006 Dec; 26(52):13411-2. PMID: 17193727
No abstract available.
6.
Fan M, Raymond L
Prog Neurobiol . 2006 Dec; 81(5-6):272-93. PMID: 17188796
Many lines of evidence support a role for neuronal damage arising as a result of excessive activation of glutamate receptors by excitatory amino acids in the pathogenesis of Huntington disease....
7.
Ordonez C, Zhai A, Camacho-Leal P, DeMarte L, Fan M, Stanners C
J Cell Physiol . 2006 Dec; 210(3):757-65. PMID: 17167768
Carcinoembryonic antigen (CEA) and CEA family member CEACAM6 are glycophosphatidyl inositol (GPI)-anchored, intercellular adhesion molecules that are up-regulated in a wide variety of human cancers, including colon, breast, and lung....