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Manjunath P Pai

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Articles 159
Citations 2736
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Recent Articles
1.
Hall 2nd R, Liu S, Pai M, Putnam W, Subramaniyan I, Kallem R, et al.
J Oncol Pharm Pract . 2025 Mar; :10781552251326045. PMID: 40080880
IntroductionExperts suggest doxorubicin clearance is decreased in women with a body mass index (BMI) of ≥35 kg/m. However, few data support this recommendation.MethodsWomen receiving doxorubicin for breast cancer in three...
2.
Hooper L, Liu S, Pai M
Pharmacotherapy . 2025 Feb; PMID: 39989027
Background: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are breakthrough medicines for obesity treatment and have rapidly gained widespread clinical application. Although GLP-1RAs are generally not associated with drug-drug interactions (DDIs) via...
3.
Nguyen-Hoang N, Liu Y, Henry N, Pai M, Zhu H, Hertz D
JCO Precis Oncol . 2025 Jan; 9:e2400380. PMID: 39889244
Purpose: Taxane-induced peripheral neuropathy (TIPN) is a dose-limiting toxicity of paclitaxel in patients with cancer. TIPN prediction is challenging although patients with higher systemic paclitaxel exposure have higher TIPN risk....
4.
Hooper L, Heung M, Kenes M, Stringer K, Mueller B, Mueller B, et al.
Clin J Am Soc Nephrol . 2025 Jan; PMID: 39888675
No abstract available.
5.
Liu S, Wang L, Miller N, Waltje A, Abdelnabi M, Zhu H, et al.
J Clin Pharmacol . 2025 Jan; PMID: 39840538
Obesity significantly influences drug pharmacokinetics (PK), which challenges optimal dosing. This study examines the effects of diet-and-exercise-induced weight loss on key drug-metabolizing enzymes and gastric emptying in patients with obesity,...
6.
Alikhani R, Horbal S, Rothberg A, Pai M
Clin Transl Sci . 2024 Dec; 17(12):e70062. PMID: 39644153
Chronological age has been the standard for quantifying the aging process. While it is simple to quantify it cannot fully discern the biological variability of aging between individuals. The growing...
7.
Schmitzberger F, Fowler J, Hsu C, Pai M, Neumar R, Meurer W, et al.
Clin Transl Sci . 2024 Nov; 17(11):e70071. PMID: 39558506
Intranasal insulin is a putative neuroprotective therapy after cardiac arrest, but safety in humans at doses extrapolated from animal models is unknown. This phase I, open-label adaptive dose-escalation study explores...
8.
Cojutti P, Pai M, Gatti M, Rinaldi M, Ambretti S, Viale P, et al.
J Antimicrob Chemother . 2024 Aug; 79(11):2801-2808. PMID: 39159014
Objectives: Ceftazidime/avibactam is a key antibiotic for carbapenemase-producing Enterobacterales (CPE) Gram-negative infections, but current dosing may be suboptimal to grant activity. This study explores the population pharmacokinetics/pharmacodynamics (PK/PD) of continuous...
9.
Olney K, Pai M, Thomas J, Burgess D, Olney W, Bruning R, et al.
Pharmacotherapy . 2024 Jul; 44(8):615-622. PMID: 39078247
Background: Daptomycin is a high-use intravenous antimicrobial agent affording the convenience of once-daily dosing. Prior studies suggest an opportunity to use a more operationally convenient fixed rather than weight-based dosing...
10.
Leino A, Takyi-Williams J, Park J, Norman S, Sun D, Farris K, et al.
Br J Clin Pharmacol . 2024 Jul; 90(11):2897-2909. PMID: 39051148
Aims: Dried blood volumetric absorptive microsamples (VAMS) may facilitate home-based sampling to enhance therapeutic drug monitoring after transplantation. This study aimed to clinically validate a liquid chromatography-tandem mass spectrometry assay...