Manjula Karpurapu
Overview
Explore the profile of Manjula Karpurapu including associated specialties, affiliations and a list of published articles.
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37
Citations
875
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Recent Articles
1.
Karpurapu M, Nie Y, Chung S, Yan J, Dougherty P, Pannu S, et al.
Front Physiol
. 2024 May;
15:1378565.
PMID: 38812883
Extracellular vesicles mediate intercellular communication by transporting biologically active macromolecules. Our prior studies have demonstrated that the nuclear factor of activated T cell cytoplasmic member 3 (NFATc3) is activated in...
2.
Karpurapu M, Kakarala K, Chung S, Nie Y, Koley A, Dougherty P, et al.
PLoS One
. 2024 Apr;
19(4):e0301904.
PMID: 38662666
Our previous research demonstrated that PU.1 regulates expression of the genes involved in inflammation in macrophages. Selective knockdown of PU.1 in macrophages ameliorated LPS-induced acute lung injury (ALI) in bone...
3.
Song M, Kim J, Gorr M, Miller R, Karpurapu M, Nguyen J, et al.
Am J Physiol Lung Cell Mol Physiol
. 2023 Sep;
325(5):L568-L579.
PMID: 37697923
The prevalence of electronic cigarette (EC) use among adult with asthma has continued to increase over time, in part due to the belief of being less harmful than smoking. However,...
4.
Nie Y, Zhai X, Li J, Sun A, Che H, Christman J, et al.
Aging Dis
. 2023 Jul;
14(4):1441-1457.
PMID: 37523510
Idiopathic pulmonary fibrosis (IPF) is a progressive and highly lethal inflammatory interstitial lung disease characterized by aberrant extracellular matrix deposition. Macrophage activation by cytokines released from repetitively injured alveolar epithelial...
5.
Nie Y, Zhai X, Li J, Sun A, Che H, Christman J, et al.
Aging Dis
. 2023 May;
PMID: 37163433
Idiopathic pulmonary fibrosis (IPF) is a progressive and highly lethal inflammatory interstitial lung disease characterized by aberrant extracellular matrix deposition. Macrophage activation by cytokines released from repetitively injured alveolar epithelial...
6.
Kim J, Stevens P, Karpurapu M, Lee H, Englert J, Yan P, et al.
Front Immunol
. 2022 Aug;
13:943554.
PMID: 35958610
Asthma is phenotypically heterogeneous with several distinctive pathological mechanistic pathways. Previous studies indicate that neutrophilic asthma has a poor response to standard asthma treatments comprising inhaled corticosteroids. Therefore, it is...
7.
Wisler J, Singh K, McCarty A, Harkless R, Karpurapu M, Hernandez E, et al.
Shock
. 2022 Jun;
57(6):218-227.
PMID: 35759303
Introduction: Survivors of sepsis exhibit persistent immunosuppression. Epigenetic events may be responsible for some of these immunosuppressive changes. During sepsis circulating exosomes contain large quantities of DNA methyltransferase (DNMT) mRNAs....
8.
Nirujogi T, Kotha S, Chung S, Reader B, Yenigalla A, Zhang L, et al.
J Innate Immun
. 2022 Apr;
14(5):555-568.
PMID: 35367992
Emerging data support the pivotal role of extracellular vesicles (EVs) in normal cellular physiology and disease conditions. However, despite their abundance, there is much less information about the lipid mediators...
9.
Christman J, Karpurapu M, Pei D
Future Med Chem
. 2021 Mar;
13(8):687-690.
PMID: 33724874
No abstract available.
10.
Varikuti S, Jha B, Holcomb E, McDaniel J, Karpurapu M, Srivastava N, et al.
Vessel Plus
. 2020 Oct;
4.
PMID: 33089078
The vascular endothelium is a vital component in maintaining the structure and function of blood vessels. The endothelial cells (ECs) mediate vital regulatory functions such as the proliferation of cells,...