Manicka V Vadhanam
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Explore the profile of Manicka V Vadhanam including associated specialties, affiliations and a list of published articles.
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42
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794
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Recent Articles
1.
Ghare S, Charpentier B, Ghooray D, Zhang J, Vadhanam M, Reddy S, et al.
Nutrients
. 2023 Oct;
15(20).
PMID: 37892472
Purpose: Chemokine-driven leukocyte infiltration and sustained inflammation contribute to alcohol-associated liver disease (ALD). Elevated hepatic CCL2 expression, seen in ALD, is associated with disease severity. However, mechanisms of CCL2 regulation...
2.
Knibbe C, Ahmed R, Wilkins F, Sharma M, Ethridge J, Morgan M, et al.
Biomedicines
. 2023 Jun;
11(6).
PMID: 37371755
Gastrointestinal (GI) complications, including motility disorders, metabolic deficiencies, and changes in gut microbiota following spinal cord injury (SCI), are associated with poor outcomes. After SCI, the autonomic nervous system becomes...
3.
Donde H, Ghare S, Joshi-Barve S, Zhang J, Vadhanam M, Gobejishvili L, et al.
Cell Mol Gastroenterol Hepatol
. 2019 Oct;
9(4):569-585.
PMID: 31654770
Methods: Mice were fed a liquid Lieber-DeCarli diet (Research Diet Inc, New Brunswick, NJ) with or without ethanol for 4 weeks. In a subset of mice, tributyrin (2 g/kg) was...
4.
Rodriguez W, Wahlang B, Wang Y, Zhang J, Vadhanam M, Joshi-Barve S, et al.
Hepatology
. 2019 May;
70(6):1958-1971.
PMID: 31081957
Alcoholic liver disease (ALD) is a major cause of liver-related mortality. There is still no US Food and Drug Administration-approved therapy for ALD, and therefore, identifying therapeutic targets is needed....
5.
Dahiya N, Chandrasekaran B, Kolluru V, Ankem M, Damodaran C, Vadhanam M
Mol Carcinog
. 2018 Aug;
57(10):1332-1341.
PMID: 30069922
Androgen ablation therapy is the primary therapeutic option for locally advanced and metastatic castration-resistant prostate cancer (CRPC). We investigated therapeutic effect of a dietary metabolite Urolithin A (UroA) and dissected...
6.
Sherwood L, Aqil F, Vadhanam M, Jeyabalan J, Munagala R, Hoetker D, et al.
Exp Mol Pathol
. 2017 Nov;
103(3):320-329.
PMID: 29157955
Cervical cancer is caused by human papillomavirus (HPV). The disease develops over many years through a series of precancerous lesions. Cervical cancer can be prevented by HPV-vaccination, screening and treatment...
7.
Aqil F, Jeyabalan J, Munagala R, Ravoori S, Vadhanam M, Schultz D, et al.
Int J Mol Sci
. 2017 Feb;
18(2).
PMID: 28212313
Scientific evidence suggests that many herbs and spices have medicinal properties that alleviate symptoms or prevent disease. In this study, we examined the chemopreventive effects of the Apiaceae spices, anise,...
8.
Munagala R, Aqil F, Jeyabalan J, Agrawal A, Mudd A, Kyakulaga A, et al.
Cancer Lett
. 2017 Feb;
393:94-102.
PMID: 28202351
Over the last two decades, berries and berry bioactives, particularly anthocyanins and their aglycones anthocyanidins (Anthos) have demonstrated excellent anti-oxidant, anti-proliferative, apoptotic and anti-inflammatory properties. However, their physicochemical and pharmacokinetic...
9.
Russell G, Gupta R, Vadhanam M
Mutat Res
. 2015 Mar;
774:25-32.
PMID: 25794985
Dibenzo[a,l]pyrene (DBP) has been found to be the most potent carcinogen of the polycyclic aromatic hydrocarbons (PAHs). Primary sources for DBP in the environment are combustion of wood and coal...
10.
Bansal S, Kausar H, Aqil F, Jeyabalan J, Vadhanam M, Gupta R, et al.
Drug Deliv Transl Res
. 2015 Mar;
1(4):332-41.
PMID: 25788367
Curcumin, an anti-oxidant, anti-inflammatory, and anti-neoplastic agent, exhibited limited oral efficacy due to its poor bioavailability. To overcome this limitation, polymeric implants for continuous systemic delivery of curcumin were developed...