Manfred Wiese
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Explore the profile of Manfred Wiese including associated specialties, affiliations and a list of published articles.
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21
Citations
561
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Recent Articles
1.
Hsu C, Gopalakrishna H, Mironova M, Lee M, Chen C, Yang H, et al.
Clin Infect Dis
. 2023 Aug;
77(Suppl 3):S245-S256.
PMID: 37579210
In a hepatitis C virus (HCV)-controlled human infection model (CHIM), healthy volunteers are inoculated with HCV and then treated. Residual hepatocellular carcinoma (HCC) risk after viral clearance is an important...
2.
Fischer J, Weber A, Bohm S, Dickhofer S, El Maadidi S, Deichsel D, et al.
Gut
. 2016 May;
66(10):1829-1837.
PMID: 27196570
Objective: As pathogen sensors, Toll-like receptors (TLR) play a role in the first defence line during HCV infection. However, the impact of the DNA sensor TLR9 on the natural course...
3.
Petersen J, Heyne R, Mauss S, Schlaak J, Schiffelholz W, Eisenbach C, et al.
Dig Dis Sci
. 2015 Nov;
61(10):3061-3071.
PMID: 26576555
Background And Aims: Multiple clinical trials have demonstrated the efficacy and safety of tenofovir disoproxil fumarate (TDF) in chronic hepatitis B (CHB). However, long-term efficacy and safety data for TDF...
4.
Wang H, El Maadidi S, Fischer J, Grabski E, Dickhofer S, Klimosch S, et al.
Hepatology
. 2015 Aug;
62(5):1375-87.
PMID: 26250868
Unlabelled: Patients carrying very rare loss-of-function mutations in interleukin-1 receptor-associated kinase 4 (IRAK4), a critical signaling mediator in Toll-like receptor signaling, are severely immunodeficient, highlighting the paramount role of IRAK...
5.
Muller T, Wiese M, Berg T
Hepatology
. 2014 Jun;
60(4):1449-50.
PMID: 24890461
No abstract available.
6.
Karlas T, Petroff D, Garnov N, Bohm S, Tenckhoff H, Wittekind C, et al.
PLoS One
. 2014 Mar;
9(3):e91987.
PMID: 24637477
Introduction: Non-invasive assessment of steatosis and fibrosis is of growing relevance in non-alcoholic fatty liver disease (NAFLD). 1H-Magnetic resonance spectroscopy (1H-MRS) and the ultrasound-based controlled attenuation parameter (CAP) correlate with...
7.
Lipskoch M, Wiese M, Timm J, Roggendorf M, Viazov S
Virol J
. 2014 Mar;
11:50.
PMID: 24628791
Background: No information is available on the possible influence of the genetic heterogeneity of major hepatitis C virus (HCV) cell receptors on selection of virus variants. Findings: Anti-D globulin preparations...
8.
Wiese M, Fischer J, Lobermann M, Gobel U, Grungreiff K, Guthoff W, et al.
Hepatology
. 2013 Aug;
59(1):49-57.
PMID: 23929603
Unlabelled: The natural course of HCV infection remains controversial. The German HCV (1b)-contaminated anti-D cohort provides an ideal population to investigate the natural course of HCV infection in a large,...
9.
Ziegler S, Ruhl M, Tenckhoff H, Wiese M, Heinemann F, Horn P, et al.
J Hepatol
. 2012 Aug;
58(1):24-30.
PMID: 22925811
Background & Aims: The antiviral immune response against HCV by CD8+ T cells plays a central role in viral containment. In a large HCV genotype 1b outbreak in Ireland, HLA-B(∗)08...
10.
Nattermann J, Timm J, Nischalke H, Olbrich A, Michalk M, Tillmann H, et al.
J Hepatol
. 2011 Jun;
55(6):1201-6.
PMID: 21703201
Background & Aims: The CCR5Δ32 mutation has been suspected to adversely affect outcomes of HCV infection, although reports have remained controversial. Here, we investigated the relative genetic contributions of the...