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Manfred Thiel

Explore the profile of Manfred Thiel including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 88
Citations 1772
Followers 0
Related Specialties
General Medicine
Allergy & Immunology
Critical Care
Top 10 Co-Authors
Alexander Chouker
Ines Kaufmann
Joerg Krebs
Holger A Lindner
Verena Schneider-Lindner
Gustav Schelling
Bianka Hahn
Franz-Simon Centner
Thomas Luecke
Jochen J Schoettler
Published In
PLoS One
J Clin Med
Anesthesiology
Shock
Int J Mol Sci
Affiliations
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Recent Articles
1.
Utilization of non-invasive ventilation before prehospital emergency anesthesia in trauma - a cohort analysis with machine learning
Luckscheiter A, Thiel M, Zink W, Eisenberger J, Viergutz T, Schneider-Lindner V
Scand J Trauma Resusc Emerg Med . 2025 Mar; 33(1):35. PMID: 40033329
Background: For preoxygenation, German guidelines consider non-invasive ventilation (NIV) as a possible method in prehospital trauma care in the absence of aspiration, severe head or face injuries, unconsciousness, or patient...
2.
Evaluation of Hypoxia Markers in Critically Ill Patients Categorized by Their Burden of Organ Dysfunction: A Novel Approach to Detect Pathophysiological and Clinical Relevance in a Secondary Analysis of a Prospective Observational Study
Centner F, Brohm K, Mindt S, Jaeger E, Hahn B, Fuderer T, et al.
Int J Mol Sci . 2025 Jan; 26(2). PMID: 39859374
In critically ill patients, compromised microcirculation causes tissue hypoxia, organ failure, and death. These pathophysiological processes occur particularly in patients with high illness severity, so reliable hypoxia biomarkers should reflect...
3.
Quantification of pulmonary edema using automated lung segmentation on computed tomography in mechanically ventilated patients with acute respiratory distress syndrome
Conrad A, Zimmermann J, Mohr D, Froelich M, Hertel A, Rathmann N, et al.
Intensive Care Med Exp . 2024 Nov; 12(1):95. PMID: 39487874
Background: Quantification of pulmonary edema in patients with acute respiratory distress syndrome (ARDS) by chest computed tomography (CT) scan has not been validated in routine diagnostics due to its complexity...
4.
Transcriptional pathways of terminal differentiation in high- and low-density blood granulocytes in sepsis
Guenther T, Coulibaly A, Velasquez S, Schulte J, Fuderer T, Sturm T, et al.
J Inflamm (Lond) . 2024 Oct; 21(1):40. PMID: 39434093
Background: Trauma and infection induce emergency granulopoiesis. Counts of immature granulocytes and transcriptional pathways of terminal granulocytic differentiation in blood are elevated in sepsis but correlate with disease severity. This...
5.
Heart rate variability as a predictor of intraoperative autonomic nervous system homeostasis
Keim O, Bolwin L, Feldmann Jr R, Thiel M, Benrath J
J Clin Monit Comput . 2024 Jul; 38(6):1305-1313. PMID: 39001955
The aim of the proof-of-concept study is to investigate the level of concordance between the heart rate variability (HRV), the EEG-based Narcotrend Index as a surrogate marker for the depth...
6.
Mortality Prediction by Kinetic Parameters of Lactate and S-Adenosylhomocysteine in a Cohort of Critically Ill Patients
Schoettler J, Brohm K, Mindt S, Jager E, Hahn B, Fuderer T, et al.
Int J Mol Sci . 2024 Jun; 25(12). PMID: 38928097
Tissue hypoxia is associated with the development of organ dysfunction and death in critically ill patients commonly captured using blood lactate. The kinetic parameters of serial lactate evaluations are superior...
7.
Sepsis and delayed cerebral ischemia are associated and have a cumulative effect on poor functional outcome in aneurysmal subarachnoid hemorrhage
Centner F, Wenz H, Oster M, Dally F, Sauter-Servaes J, Pelzer T, et al.
Front Neurol . 2024 Jun; 15:1393989. PMID: 38882701
Objective: Although sepsis and delayed cerebral ischemia (DCI) are severe complications in patients with aneurysmal subarachnoid hemorrhage (aSAH) and share pathophysiological features, their interrelation and additive effect on functional outcome...
8.
Effects of prone positioning on lung mechanical power components in patients with acute respiratory distress syndrome: a physiologic study
Boesing C, Krebs J, Conrad A, Otto M, Beck G, Thiel M, et al.
Crit Care . 2024 Mar; 28(1):82. PMID: 38491457
Background: Prone positioning (PP) homogenizes ventilation distribution and may limit ventilator-induced lung injury (VILI) in patients with moderate to severe acute respiratory distress syndrome (ARDS). The static and dynamic components...
9.
Pneumonia in the first week after polytrauma is associated with reduced blood levels of soluble herpes virus entry mediator
Schaefer N, Lindner H, Hahn B, Schefzik R, Velasquez S, Schulte J, et al.
Front Immunol . 2024 Jan; 14:1259423. PMID: 38187375
Background: Pneumonia develops frequently after major surgery and polytrauma and thus in the presence of systemic inflammatory response syndrome (SIRS) and organ dysfunction. Immune checkpoints balance self-tolerance and immune activation....
10.
Preload Responsiveness in Patients With Acute Respiratory Distress Syndrome Managed With Extracorporeal Membrane Oxygenation
Loosen G, Conrad A, Essert N, Boesing C, Hagmann M, Thiel M, et al.
ASAIO J . 2023 Nov; 70(1):53-61. PMID: 37934718
A restrictive fluid strategy is recommended in patients with acute respiratory distress syndrome (ARDS) managed with venovenous extracorporeal membrane oxygenation (VV ECMO). However, there are no established predictors for preload...