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Manel Jendoubi

Explore the profile of Manel Jendoubi including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 247
Followers 0
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Recent Articles
1.
Le Maitre M, Guerrier T, Collet A, Derhourhi M, Meneboo J, Toussaint B, et al.
Front Immunol . 2024 Aug; 15:1373464. PMID: 39185406
Introduction: In systemic sclerosis (SSc), B-cells are activated and present in the skin and lung of patients where they can interact with fibroblasts. The precise impact and mechanisms of the...
2.
Speca S, Farhat M, Jendoubi M, Guerrier T, Sanges S, Staumont-Salle D, et al.
Sci Rep . 2023 Sep; 13(1):15102. PMID: 37700078
Systemic sclerosis (SSc) is the most severe systemic autoimmune disease with currently no cure. Intravenous immunoglobulins (IVIg) are an attractive candidate in this disease to counteract inflammation and fibrosis but...
3.
Ortega-Ferreira C, Soret P, Robin G, Speca S, Hubert S, Le Gall M, et al.
Nat Commun . 2023 Aug; 14(1):5291. PMID: 37652913
Systemic sclerosis (SSc) is an autoimmune, inflammatory and fibrotic disease with limited treatment options. Developing new therapies is therefore crucial to address patient needs. To this end, we focused on...
4.
Sanges S, Guerrier T, Duhamel A, Guilbert L, Hauspie C, Largy A, et al.
Front Immunol . 2022 Aug; 13:954007. PMID: 35967377
Introduction: Soluble markers of B cell activation are interesting diagnostic and prognostic tools in autoimmune diseases. Data in systemic sclerosis (SSc) are scarce and few studies focused on their association...
5.
Chepy A, Vivier S, Bray F, Ternynck C, Meneboo J, Figeac M, et al.
Front Immunol . 2022 Jul; 13:904631. PMID: 35844491
Autoantibodies (Aabs) are frequent in systemic sclerosis (SSc). Although recognized as potent biomarkers, their pathogenic role is debated. This study explored the effect of purified immunoglobulin G (IgG) from SSc...
6.
Ledoult E, Jendoubi M, Collet A, Guerrier T, Largy A, Speca S, et al.
Sci Rep . 2022 Jul; 12(1):11748. PMID: 35817787
We provide an original multi-stage approach identifying a gene signature to assess murine fibroblast polarization. Prototypic polarizations (inflammatory/fibrotic) were induced by seeded mouse embryonic fibroblasts (MEFs) with TNFα or TGFß1,...
7.
Chepy A, Veron M, Gautier S, Farhat M, Pokeerbux R, Venturelli G, et al.
Allergy Asthma Proc . 2022 Mar; 43(2):155-162. PMID: 35317893
A differential diagnosis between angiotensin-converting enzyme inhibitor (ACEi) angioedema (AE) and histaminergic AE (hAE) might be challenging. Follow-up data may help discriminate these conditions but are scarcely reported. To report...
8.
Vivier S, Chepy A, Bray F, Guerrier T, Speca S, Flament S, et al.
Proteomics . 2021 Oct; 22(3):e2100116. PMID: 34665929
Fibroblasts (Fb) are key effector cells in systemic sclerosis (SSc). Fb stimulation with transforming growth factor beta 1 (TGF-β1) is considered as a positive control in studies assessing fibrogenesis. The...
9.
Sanges S, Jendoubi M, Kavian N, Hauspie C, Speca S, Crave J, et al.
Front Immunol . 2017 Feb; 8:53. PMID: 28223983
Introduction: During systemic sclerosis (SSc), peripheral B cells display alterations in subset homeostasis and functional properties and are a promising therapeutic target. However, there is only few data regarding whether...
10.
Ballot C, Martoriati A, Jendoubi M, Buche S, Formstecher P, Mortier L, et al.
Mar Drugs . 2014 Jan; 12(2):779-98. PMID: 24473175
Lamellarin D (LamD) is a marine alkaloid with broad spectrum antitumor activities. Multiple intracellular targets of LamD, which affect cancer cell growth and induce apoptosis, have been identified. These include...