Manel Jendoubi
Overview
Explore the profile of Manel Jendoubi including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
14
Citations
247
Followers
0
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Recent Articles
11.
Corazao-Rozas P, Guerreschi P, Jendoubi M, Andre F, Jonneaux A, Scalbert C, et al.
Oncotarget
. 2013 Oct;
4(11):1986-98.
PMID: 24161908
Vemurafenib/PLX4032, a selective inhibitor of mutant BRAFV600E, constitutes a paradigm shift in melanoma therapy. Unfortunately, acquired resistance, which unavoidably occurs, represents one major limitation to clinical responses. Recent studies have...
12.
Kluza J, Corazao-Rozas P, Touil Y, Jendoubi M, Maire C, Guerreschi P, et al.
Cancer Res
. 2012 Aug;
72(19):5035-47.
PMID: 22865452
Cancer cells can undergo a metabolic reprogramming from oxidative phosphorylation to glycolysis that allows them to adapt to nutrient-poor microenvironments, thereby imposing a selection for aggressive variants. However, the mechanisms...
13.
Ballot C, Jendoubi M, Kluza J, Jonneaux A, Laine W, Formstecher P, et al.
Apoptosis
. 2011 Dec;
17(4):364-76.
PMID: 22127645
F14512, an epipodophyllotoxin derivative equipped with a spermine moiety, is selectively taken up by the polyamine transport system over-active in tumor cells. F14512 was identified as a selective anticancer agent...
14.
Kluza J, Jendoubi M, Ballot C, Dammak A, Jonneaux A, Idziorek T, et al.
PLoS One
. 2011 Jul;
6(7):e21924.
PMID: 21789194
Challenges today concern chronic myeloid leukemia (CML) patients resistant to imatinib. There is growing evidence that imatinib-resistant leukemic cells present abnormal glucose metabolism but the impact on mitochondria has been...